Current Topics in Microbiology and Immunology

Henipavirus

Ecology, Molecular Virology, and Pathogenesis

Editors: Lee, Benhur, Rota, Paul A. (Eds.)

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About this book

Henipaviruses form a new genus of emerging paramyxoviruses that are the deadliest human pathogens within the Paramyxoviridae family. This volume deals with the many facets of henipavirus biology, and covers our current understanding regarding the ecology, molecular virology, and pathogenesis of henipavirus infections. It is an international effort written by a multidisciplinary panel of experts at the front lines of research into this lethal emerging group of paramyxoviruses. The first section introduces the epidemiology and ecology of Nipah and Hendra viruses in their respective endemic areas, including a first-hand account of the discovery of Nipah virus during its initial outbreak in Malaysia; the next section documents the molecular virology of henipaviruses, and the substantial advances made towards understanding the unique features of henipavirus entry and tropism; and this is followed by accounts of the clinical and pathologic features of henipavirus infections in their human and naturally infected animal hosts. The next sections on pathogenesis provide a comprehensive reference on how henipaviruses counteract the innate immune system, and the relevant pathogenic features in animal challenge models developed to test potential therapeutic strategies. The final sections describe our current and future capabilities for diagnosis and control, including an account of potentially effective immunization strategies that are currently being tested. 

 

This book will not only serve as a useful reference for the henipavirus field; it will be useful to basic and animal virologists, ecologists, epidemiologists, physicians, and others interested in emerging infectious viral diseases, as it showcases the multidisciplinary efforts required to understand the genesis, spread and hopefully, control, of a group of lethal emerging zoonotic pathogens.  

Table of contents (12 chapters)

  • Introduction: Nipah Virus—Discovery and Origin

    Chua, Kaw Bing

    Pages 1-9

  • Ecological Aspects of Hendra Virus

    Field, Hume (et al.)

    Pages 11-23

  • Epidemiology of Henipavirus Disease in Humans

    Luby, Stephen P. (et al.)

    Pages 25-40

  • Molecular Virology of the Henipaviruses

    Rota, Paul A. (et al.)

    Pages 41-58

  • Henipavirus Receptor Usage and Tropism

    Pernet, Olivier (et al.)

    Pages 59-78

Buy this book

eBook $169.00
price for USA (gross)
  • ISBN 978-3-642-29819-6
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $219.00
price for USA
  • ISBN 978-3-642-29818-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $219.00
price for USA
  • ISBN 978-3-642-44019-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Henipavirus
Book Subtitle
Ecology, Molecular Virology, and Pathogenesis
Editors
  • Benhur Lee
  • Paul A. Rota
Series Title
Current Topics in Microbiology and Immunology
Series Volume
359
Copyright
2012
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-29819-6
DOI
10.1007/978-3-642-29819-6
Hardcover ISBN
978-3-642-29818-9
Softcover ISBN
978-3-642-44019-9
Series ISSN
0070-217X
Edition Number
1
Number of Pages
XII, 228
Topics