Springer Series in Bio-/Neuroinformatics

Computational Methods to Study the Structure and Dynamics of Biomolecules and Biomolecular Processes

From Bioinformatics to Molecular Quantum Mechanics

Editors: Liwo, Adam (Ed.)

  • Comprehensive overview of modern computer-based techniques for computing the structure, properties and dynamics of biomolecules and biomolecular processes
  • Introduces theory and practice of molecular simulations, bioinformatics methods  as well as selected applications of molecular quantum mechanics to the study of biological systems
  • Edited and written by leading scientists in the field
see more benefits

Buy this book

eBook $179.00
price for USA (gross)
  • ISBN 978-3-642-28554-7
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $229.00
price for USA
  • ISBN 978-3-642-28553-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $229.00
price for USA
  • Customers within the U.S. and Canada please contact Customer Service at 1-800-777-4643, Latin America please contact us at +1-212-460-1500 (Weekdays 8:30am – 5:30pm ET) to place your order.
  • Due: November 11, 2016
  • ISBN 978-3-662-50847-3
  • Free shipping for individuals worldwide
About this book

Since the second half of the 20th century machine computations have played a critical role in science and engineering. Computer-based techniques have become especially important in molecular biology, since they often represent the only viable way to gain insights into the behavior of a biological system as a whole. The complexity of biological systems, which usually needs to be analyzed on different time- and size-scales and with different levels of accuracy, requires the application of different approaches, ranging from comparative analysis of sequences and structural databases, to the analysis of networks of interdependence between cell components and processes, through coarse-grained modeling to atomically detailed simulations, and finally to molecular quantum mechanics.

This book provides a comprehensive overview of modern computer-based techniques for computing the structure, properties and dynamics of biomolecules and biomolecular processes. The twenty-two chapters, written by scientists from all over the world, address the theory and practice of computer simulation techniques in the study of biological phenomena. The chapters are grouped into four thematic sections dealing with the following topics: the methodology of molecular simulations; applications of molecular simulations; bioinformatics methods and use of experimental information in molecular simulations; and selected applications of molecular quantum mechanics. The book includes an introductory chapter written by Harold A. Scheraga, one of the true pioneers in simulation studies of biomacromolecules.

Reviews

From the book reviews:

“The purpose of the book is to provide an overview of modern methods and techniques for simulating and modeling biological systems. … the book is an excellent introductory text that could be very useful for graduate students who are just starting research projects and need to establish a broader view of simulation methodologies.” (Alexander Tzanov, Computing Reviews, June, 2014)


Table of contents (22 chapters)

  • Simulations of the Folding of Proteins: A Historical Perspective

    Scheraga, Harold A.

    Pages 1-23

  • Coarse-Grained Protein Models in Structure Prediction

    Blaszczyk, Maciej (et al.)

    Pages 25-53

  • Coarse-Grained Modeling of Protein Dynamics

    Kmiecik, Sebastian (et al.)

    Pages 55-79

  • Physics-Based Modeling of Side Chain - Side Chain Interactions in the UNRES Force Field

    Makowski, Mariusz

    Pages 81-107

  • Modeling Nucleic Acids at the Residue-Level Resolution

    Leonarski, Filip (et al.)

    Pages 109-149

Buy this book

eBook $179.00
price for USA (gross)
  • ISBN 978-3-642-28554-7
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $229.00
price for USA
  • ISBN 978-3-642-28553-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $229.00
price for USA
  • Customers within the U.S. and Canada please contact Customer Service at 1-800-777-4643, Latin America please contact us at +1-212-460-1500 (Weekdays 8:30am – 5:30pm ET) to place your order.
  • Due: November 11, 2016
  • ISBN 978-3-662-50847-3
  • Free shipping for individuals worldwide
Loading...

Recommended for you

Loading...

Bibliographic Information

Bibliographic Information
Book Title
Computational Methods to Study the Structure and Dynamics of Biomolecules and Biomolecular Processes
Book Subtitle
From Bioinformatics to Molecular Quantum Mechanics
Editors
  • Adam Liwo
Series Title
Springer Series in Bio-/Neuroinformatics
Series Volume
1
Copyright
2014
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-28554-7
DOI
10.1007/978-3-642-28554-7
Hardcover ISBN
978-3-642-28553-0
Softcover ISBN
978-3-662-50847-3
Series ISSN
2193-9349
Edition Number
1
Number of Pages
XIV, 810
Number of Illustrations and Tables
120 b/w illustrations, 90 illustrations in colour
Topics