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Theranostics, Gallium-68, and Other Radionuclides

A Pathway to Personalized Diagnosis and Treatment

  • Conference proceedings
  • © 2013

Overview

Editors:
  1. Richard P. Baum

    1. , THERANOSTICS Center for Molecular,, ENETS Center of Excellence, Bad Berka, Germany

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    You can also search for this editor in PubMed   Google Scholar

  2. Frank Rösch

    1. Inst. Kernchemie, Universität Mainz, Mainz, Germany

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    You can also search for this editor in PubMed   Google Scholar

  • Examines in detail the latest developments in theranostics for neuroendocrine tumors and other diseases
  • Covers a wide spectrum of topics, from radiochemistry to clinical applications
  • Focuses on gallium-68 but also considers other PET radionuclides
  • Includes supplementary material: sn.pub/extras

Part of the book series: Recent Results in Cancer Research (RECENTCANCER, volume 194)

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Table of contents (34 papers)

  1. Front Matter

    Pages i-xviii
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  3. Radiochemistry and Radiopharmacy

    1. Front Matter

      Pages 99-99
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    2. The Diversity of 68Ga-Based Imaging Agents

      • Irina Velikyan
      Pages 101-131

    3. Nanoparticles and Phage Display Selected Peptides for Imaging and Therapy of Cancer

      • Cathy S. Cutler, Nripen Chanda, Ravi Shukla, Nebiat Sisay, Melchor Cantorias, Ajit Zambre et al.
      Pages 133-147

    4. “Click”-Cyclized 68Ga-Labeled Peptides for Molecular Imaging and Therapy: Synthesis and Preliminary In Vitro and In Vivo Evaluation in a Melanoma Model System

      • Molly E. Martin, M. Sue O’Dorisio, Whitney M. Leverich, Kyle C. Kloepping, Susan A. Walsh, Michael K. Schultz
      Pages 149-175

    5. Early Experience with 68Ga-DOTATATE Preparation

      • Maung Maung Saw
      Pages 177-188

    6. 68Ga-Radiopharmaceuticals for PET Imaging of Infection and Inflammation

      • Vijay Kumar, Dilip K. Boddeti
      Pages 189-219

    7. 68Ga-Labeled Bombesin Analogs for Receptor-Mediated Imaging

      • Raunak Varshney, Puja P. Hazari, P. Fernandez, J. Schulz, M. Allard, Anil K. Mishra
      Pages 221-256

    8. A Novel 68Ga-Labeled Pteroic Acid-Based PET Tracer for Tumor Imaging via the Folate Receptor

      • Berit Kühle, Cristina Müller, Tobias L. Ross
      Pages 257-267

    9. Measurement of Protein Synthesis: In Vitro Comparison of 68Ga-DOTA-Puromycin, [3H]Tyrosine, and 2-Fluoro-[3H]tyrosine

      • Sebastian Eigner, Denis R. Beckford Vera, Marco Fellner, Natalia S. Loktionova, Markus Piel, Frantisek Melichar et al.
      Pages 269-283

    10. Hypoxia Imaging Agents Labeled with Positron Emitters

      • Lathika Hoigebazar, Jae Min Jeong
      Pages 285-299

    11. 177Lu/90Y Intermediate-Affinity Monoclonal Antibodies Targeting EGFR and HER2/c-neu: Preparation and Preclinical Evaluation

      • Denis R. Beckford Vera, Sebastian Eigner, Katerina Eigner Henke, Rene Leyva Montaña, Frantisek Melichar, Milos Beran
      Pages 301-317

  4. Molecular Imaging Using 68Ga labeled Tracers

    1. Front Matter

      Pages 319-319
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Keywords

About this book

This book is based on contributions presented at the 1st World Congress on Gallium-68 and Peptide Receptor Radionuclide Therapy, which examined recent developments in theranostics – the emerging field of molecular targeting of vectors that can be used for both diagnosis and therapy, when modified accordingly. The focus of this book is on the rapidly developing research into and clinical applications of gallium-68 and other generator-produced PET radionuclides in the personalized diagnosis and treatment of neuroendocrine tumors and other diseases. In addition, new PET radiopharmaceuticals are considered, and the latest ideas and concepts, presented. Theranostics embodies both molecular and personalized medicine. It is at the cutting edge of medicine, and the contents of this volume will be of interest to chemists, physicians, and investigators dealing with generators, PET radiochemistry, molecular imaging, and radionuclide therapy.

Reviews

From the reviews:

“The general themes of this book (theranostics and peptide receptor–targeted radiotherapy) derive from evolving successes in the use of generator-produced 68Ga for molecular imaging of disease. … This book is an excellent resource for investigators interested in gaining a detailed understanding of the state of the art in 68Ga and peptide receptor radionuclide therapy–based theranostics for preclinical and emerging clinical applications.” (Michael K. Schultz, The Journal of Nuclear Medicine, Vol. 54 (4), April, 2013)

Editors and Affiliations

  • , THERANOSTICS Center for Molecular,, ENETS Center of Excellence, Bad Berka, Germany

    Richard P. Baum

  • Inst. Kernchemie, Universität Mainz, Mainz, Germany

    Frank Rösch

Bibliographic Information

  • Book Title: Theranostics, Gallium-68, and Other Radionuclides

  • Book Subtitle: A Pathway to Personalized Diagnosis and Treatment

  • Editors: Richard P. Baum, Frank Rösch

  • Series Title: Recent Results in Cancer Research

  • DOI: https://doi.org/10.1007/978-3-642-27994-2

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer-Verlag Berlin Heidelberg 2013

  • Hardcover ISBN: 978-3-642-27993-5Published: 23 August 2012

  • Softcover ISBN: 978-3-642-44160-8Published: 20 September 2014

  • eBook ISBN: 978-3-642-27994-2Published: 23 August 2012

  • Series ISSN: 0080-0015

  • Series E-ISSN: 2197-6767

  • Edition Number: 1

  • Number of Pages: XVIII, 578

  • Topics: Oncology, Nuclear Medicine, Neuroradiology, Radiotherapy, Molecular Medicine

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