Research and Perspectives in Alzheimer's Disease

Protein Quality Control in Neurodegenerative Diseases

Editors: Morimoto, Richard I., Christen, Yves (Eds.)

  • Written by leading experts in the fields Neuroscience and Endocrinology
  • Provides topical research results
  • Another excellent group of authors and their chapters collected by Fondation Ipsen 
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eBook $149.00
price for USA (gross)
  • ISBN 978-3-642-27928-7
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $189.00
price for USA
  • ISBN 978-3-642-27927-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $189.00
price for USA
  • ISBN 978-3-642-44706-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

The health of the proteome depends upon protein quality control to regulate the proper synthesis, folding, translocation, and clearance of proteins. The cell is challenged constantly by environmental and physiological stress, aging, and the chronic expressions of disease associated misfolded proteins. Substantial evidence supports the hypothesis that the expression of damaged proteins initiates a cascade of molecular events that leads to Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, Huntington's disease, and other diseases of protein conformation.

Reviews

From the reviews:

“This is a very good cutting edge book of scholarly import on the functioning of molecules and signal transduction in both neurodegeneration and neuroprotection. … I recommend this book highly to scientists in disease pathophysiology work.” (Joseph J. Grenier, Amazon.com, June, 2014)

Table of contents (10 chapters)

  • The regulation and function of the heat shock response

    Guisbert, Eric (et al.)

    Pages 1-18

  • The endoplasmic reticulum unfolded protein response and neurodegeneration

    Ron, David

    Pages 19-35

  • Proteostasis and the aging pathways

    Nicastro, Ian (et al.)

    Pages 37-52

  • The membrane sources of macroautophagy

    Klionsky, Daniel J. (et al.)

    Pages 53-61

  • Selective autophagy in cellular quality control

    Kaushik, Susmita (et al.)

    Pages 63-75

Buy this book

eBook $149.00
price for USA (gross)
  • ISBN 978-3-642-27928-7
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $189.00
price for USA
  • ISBN 978-3-642-27927-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $189.00
price for USA
  • ISBN 978-3-642-44706-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Protein Quality Control in Neurodegenerative Diseases
Editors
  • Richard I. Morimoto
  • Yves Christen
Series Title
Research and Perspectives in Alzheimer's Disease
Copyright
2013
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-27928-7
DOI
10.1007/978-3-642-27928-7
Hardcover ISBN
978-3-642-27927-0
Softcover ISBN
978-3-642-44706-8
Series ISSN
0945-6066
Edition Number
1
Number of Pages
XII, 136
Topics