Topics in Current Chemistry

Fragment-Based Drug Discovery and X-Ray Crystallography

Editors: Davies, Thomas G., Hyvönen, Marko (Eds.)

  • This series presents critical reviews of the present position and future trends in modern chemical research
  • Short and concise reports on chemistry, each written by the world renowned experts
  • Still valid and useful after 5 or 10 years
  • More information as well as the electronic version of the whole content available at: springerlink.com
see more benefits

Buy this book

eBook $269.00
price for USA (gross)
  • ISBN 978-3-642-27540-1
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $349.00
price for USA
  • ISBN 978-3-642-27539-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $349.00
price for USA
  • ISBN 978-3-642-44635-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Introduction to Fragment-Based Drug Discovery, by Daniel A. Erlanson

Fragment Screening Using X-Ray Crystallography, by Thomas G. Davies and Ian J. Tickle

Hsp90 Inhibitors and Drugs from Fragment and Virtual Screening, by Stephen Roughley, Lisa Wright, Paul Brough, Andrew Massey and Roderick E. Hubbard

Combining NMR and X-ray Crystallography in Fragment-Based Drug Discovery: Discovery of Highly Potent and Selective BACE-1 Inhibitors, by Daniel F. Wyss, Yu-Sen Wang, Hugh L. Eaton, Corey Strickland, Johannes H. Voigt, Zhaoning Zhu and Andrew W. Stamford

Combining Biophysical Screening and X-Ray Crystallography for Fragment-Based Drug Discovery, by Michael Hennig, Armin Ruf and Walter Huber

Targeting Protein–Protein Interactions and Fragment-Based Drug Discovery, by Eugene Valkov, Tim Sharpe, May Marsh, Sandra Greive and Marko Hyvönen

Fragment Screening and HIV Therapeutics, by Joseph D. Bauman, Disha Patel and Eddy Arnold

Fragment-Based Approaches and Computer-Aided Drug Discovery, by Didier Rognan

Table of contents (8 chapters)

  • Introduction to Fragment-Based Drug Discovery

    Erlanson, Daniel A.

    Pages 1-32

  • Fragment Screening Using X-Ray Crystallography

    Davies, Thomas G. (et al.)

    Pages 33-59

  • Hsp90 Inhibitors and Drugs from Fragment and Virtual Screening

    Roughley, Stephen (et al.)

    Pages 61-82

  • Combining NMR and X-ray Crystallography in Fragment-Based Drug Discovery: Discovery of Highly Potent and Selective BACE-1 Inhibitors

    Wyss, Daniel F. (et al.)

    Pages 83-114

  • Combining Biophysical Screening and X-Ray Crystallography for Fragment-Based Drug Discovery

    Hennig, Michael (et al.)

    Pages 115-143

Buy this book

eBook $269.00
price for USA (gross)
  • ISBN 978-3-642-27540-1
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $349.00
price for USA
  • ISBN 978-3-642-27539-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $349.00
price for USA
  • ISBN 978-3-642-44635-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Loading...

Recommended for you

Loading...

Bibliographic Information

Bibliographic Information
Book Title
Fragment-Based Drug Discovery and X-Ray Crystallography
Editors
  • Thomas G. Davies
  • Marko Hyvönen
Series Title
Topics in Current Chemistry
Series Volume
317
Copyright
2012
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-27540-1
DOI
10.1007/978-3-642-27540-1
Hardcover ISBN
978-3-642-27539-5
Softcover ISBN
978-3-642-44635-1
Series ISSN
0340-1022
Edition Number
1
Number of Pages
XII, 228
Topics