RNA Technologies

From Nucleic Acids Sequences to Molecular Medicine

Editors: Erdmann (Deceased), Volker A., Barciszewski, Jan (Eds.)

  • The book covers hot topics such as small interference RNAs for gene silencing in molecular biology and medicine
  • Written by leading experts in the field
  • With numerous illustrations
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eBook $219.00
price for USA (gross)
  • ISBN 978-3-642-27426-8
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $279.00
price for USA
  • ISBN 978-3-642-27425-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $279.00
price for USA
  • ISBN 978-3-642-43083-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Despite a half century of structural, biophysical and biochemical investigations of ribonucleic acids, they are still mysterious. RNAs stand at fertile crossroads of disciplines, integrating concepts from genomics, proteomics, dynamics as well as biochemistry and molecular biology. From 20 years it is clear, that genetic regulation of eukaryotic organisms has been misunderstood for the last years that the expression of genetic information is effected only by proteins. Basic understanding of nucleic acids has enhanced our foundation to probe novel biological functions. This is especially evident for RNA molecules whose functionality, maturation, and regulation require formation of correct secondary structure through encoded base-pairing interactions.

Table of contents (26 chapters)

  • RNAissance

    Brosius, Juergen

    Pages 1-18

  • Nucleic Acids as Therapeutics

    Pushpendra, Saraswat (et al.)

    Pages 19-45

  • Thio Effects as a Tool for Mechanistic Studies of the Cleavage of RNA Phosphodiester Bonds: The Chemical Basis

    Ora, Mikko (et al.)

    Pages 47-65

  • Off-Target Effects and Safety Aspects of Phosphorothioate Oligonucleotides

    Stessl, Martina (et al.)

    Pages 67-83

  • Oligonucleotide Conjugates: Rationale, Synthesis, and Applications

    Singh, Yashveer (et al.)

    Pages 85-120

Buy this book

eBook $219.00
price for USA (gross)
  • ISBN 978-3-642-27426-8
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $279.00
price for USA
  • ISBN 978-3-642-27425-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $279.00
price for USA
  • ISBN 978-3-642-43083-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
From Nucleic Acids Sequences to Molecular Medicine
Editors
  • Volker A. Erdmann (Deceased)
  • Jan Barciszewski
Series Title
RNA Technologies
Copyright
2012
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-27426-8
DOI
10.1007/978-3-642-27426-8
Hardcover ISBN
978-3-642-27425-1
Softcover ISBN
978-3-642-43083-1
Series ISSN
2197-9731
Edition Number
1
Number of Pages
X, 654
Topics