Current Topics in Microbiology and Immunology

Notch Regulation of the Immune System

Editors: Radtke, Freddy (Ed.)

  • An interesting issue of relatively short, thought-provoking articles on specific aspects of Notch signalling within the immune system

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eBook $169.00
price for USA (gross)
  • ISBN 978-3-642-24294-6
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $219.00
price for USA
  • ISBN 978-3-642-24293-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $219.00
price for USA
  • ISBN 978-3-642-43408-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Notch signaling regulates many cell fate decision and differentiation processes during embryonic development and tissue homeostasis. Moreover, disregulation of the pathway is associated with human disorders and cancer. In the last 15 years it became evident that Notch plays important roles in the hematopoietic system as well as in the regulation of immune responses. This special issue on Notch regulation of the immune system summarizes recent advances and covers multiple aspects of Notch signaling within the hematopoietic and the immune system.  This issue covers subjects including Notch function in embryonic and adult hematopoietic stem cells, lymphocyte development and function as well as in T cell leukemia.

Table of contents (9 chapters)

  • The Notch Pathway in Hematopoietic Stem Cells

    Bigas, Anna (et al.)

    Pages 1-18

  • Notch Receptor-Ligand Interactions During T Cell Development, a Ligand Endocytosis-Driven Mechanism

    Shah, Divya K. (et al.)

    Pages 19-46

  • Notch1 and IL-7 Receptor Signalling in Early T-cell Development and Leukaemia

    González-García, Sara (et al.)

    Pages 47-73

  • Notch Signaling During Human T cell Development

    Taghon, Tom (et al.)

    Pages 75-97

  • Canonical and Non-Canonical Notch Signaling in CD4+ T Cells

    Minter, Lisa M. (et al.)

    Pages 99-114

Buy this book

eBook $169.00
price for USA (gross)
  • ISBN 978-3-642-24294-6
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $219.00
price for USA
  • ISBN 978-3-642-24293-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $219.00
price for USA
  • ISBN 978-3-642-43408-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Notch Regulation of the Immune System
Editors
  • Freddy Radtke
Series Title
Current Topics in Microbiology and Immunology
Series Volume
360
Copyright
2012
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-24294-6
DOI
10.1007/978-3-642-24294-6
Hardcover ISBN
978-3-642-24293-9
Softcover ISBN
978-3-642-43408-2
Series ISSN
0070-217X
Edition Number
1
Number of Pages
XII, 184
Topics