Recent Results in Cancer Research

Prevention of Bone Metastases

Editors: joerger, markus, Gnant, Michael (Eds.)

  • Overview of current knowledge regarding the prevention of bone metastases in a variety of cancers
  • Detailed analysis of the efficacy of bisphosphonates, including in combination with cytostatics
  • Written by acknowledged experts in the field
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  • ISBN 978-3-642-21892-7
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About this book

Bone metastases continue to be a major cause of morbidity in cancer patients, but improved understanding of the biology of bone metastases has led to the identification of drugs that are of potential value in not only their treatment but also their prevention. This book, written by recognized experts in the field, provides a detailed overview of current knowledge on this subject. One important focus of the book is the efficacy of bisphosphonates in preventing bone metastases in patients with breast, lung, and prostate cancer and disease progression in cases of multiple myeloma. The combined use of bisphosphonates and cytostatics is also discussed, with a report on first clinical data. Further topics addressed include the significance of the bone microenvironment, special issues in the elderly patient, the use of bone turnover markers, and initial findings obtained with denosumab.

Table of contents (11 chapters)

  • Preclinical Models that Illuminate the Bone Metastasis Cascade

    Horst, Geertje (et al.)

    Pages 1-31

  • The Role of Bone Microenvironment, Vitamin D and Calcium

    Santini, Daniele (et al.)

    Pages 33-64

  • Bisphosphonates: Prevention of Bone Metastases in Breast Cancer

    Gnant, Michael (et al.)

    Pages 65-91

  • Bisphosphonates: Prevention of Bone Metastases in Lung Cancer

    Decoster, Lynn (et al.)

    Pages 93-108

  • Bisphosphonates: Prevention of Bone Metastases in Prostate Cancer

    Saad, Fred (et al.)

    Pages 109-126

Buy this book

eBook $179.00
price for USA (gross)
  • ISBN 978-3-642-21892-7
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $229.00
price for USA
  • ISBN 978-3-642-21891-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $229.00
price for USA
  • ISBN 978-3-642-44614-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Rent the ebook  
  • Rental duration: 1 or 6 month
  • low-cost access
  • online reader with highlighting and note-making option
  • can be used across all devices
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Bibliographic Information

Bibliographic Information
Book Title
Prevention of Bone Metastases
Editors
  • markus joerger
  • Michael Gnant
Series Title
Recent Results in Cancer Research
Series Volume
192
Copyright
2012
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-21892-7
DOI
10.1007/978-3-642-21892-7
Hardcover ISBN
978-3-642-21891-0
Softcover ISBN
978-3-642-44614-6
Series ISSN
0080-0015
Edition Number
1
Number of Pages
X, 234
Topics