Editors:
- Provides new insights into aneurysm aetiology and behavior
- Brings together a unique blend of expertise in experimental, computational and tissue biomechanics
Part of the book series: Studies in Mechanobiology, Tissue Engineering and Biomaterials (SMTEB, volume 7)
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Table of contents (13 chapters)
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Front Matter
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Back Matter
About this book
Cardiovascular disease is the leading cause of morbidity and premature death of modern era medicine. It is estimated that approximately 81 million people in the United States (US) currently have one or more of the many forms of cardiovascular disease, resulting in 1 in every 2.8 deaths, or 900,000 deaths per year. 40% of all deaths in Europe are a result of cardiovascular disease in people under the age of 75. Aneurysms form a significant portion of these cardiovascular related deaths and are defined as a permanent and irreversible localised dilation of a blood vessel greater than 50% of its normal diameter. Although aneurysms can form in any blood vessel, the more lethal aneurysms develop in the cranial arteries, and in the thoracic aorta and abdominal aorta. Frequently aneurysms are undetected and if left untreated may eventually expand until rupture with very high levels of morbidity and mortality. The biomechanics and mechanobiology of aneursymal diseases are not fully understood and this monograph aims to provide new insights into aneurysm aetiology and behavior based on the most recent biomechanics research related to this important topic. The contributors to this volume bring together a unique blend of expertise in experimental, computational and tissue biomechanics relating to aneurysm behavior and enable the reader to gain a fresh understanding of key factors influencing aneurysm behavior and treatment. Biological risk factors such as tobacco smoking, sex, age, hypertension, family history and mechanobiological risk factors such as aneurysm geometry and shape as well as mechanical properties of the diseased tissues are considered in detail as are many of the diagnostic and treatment options.
Editors and Affiliations
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Dept. Mechanical and Aerospace, Engineering, University Limerick, Limerick, Ireland
Tim McGloughlin
Bibliographic Information
Book Title: Biomechanics and Mechanobiology of Aneurysms
Editors: Tim McGloughlin
Series Title: Studies in Mechanobiology, Tissue Engineering and Biomaterials
DOI: https://doi.org/10.1007/978-3-642-18095-8
Publisher: Springer Berlin, Heidelberg
eBook Packages: Engineering, Engineering (R0)
Copyright Information: Springer-Verlag Berlin Heidelberg 2011
Hardcover ISBN: 978-3-642-18094-1Published: 15 September 2011
Softcover ISBN: 978-3-642-27075-8Published: 27 November 2013
eBook ISBN: 978-3-642-18095-8Published: 15 September 2011
Series ISSN: 1868-2006
Series E-ISSN: 1868-2014
Edition Number: 1
Number of Pages: XIV, 426
Topics: Biomedical Engineering and Bioengineering, Biomaterials, Human Physiology, Cardiac Surgery, Solid Mechanics