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Studies in Mechanobiology, Tissue Engineering and Biomaterials

Myocardial Tissue Engineering

Editors: Boccaccini, Aldo R., Harding, Sian (Eds.)

  • Gives an insight into clinical trials and novel cell sources for cell therapy
  • Covers a complete range of biomaterials, examining different aspects of their application
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  • ISBN 978-3-642-18056-9
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Hardcover $199.00
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  • ISBN 978-3-642-18055-2
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  • ISBN 978-3-642-26978-3
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About this book

Myocardial tissue engineering (MTE), a strategy that uses materials or material/cell constructs to prolong patients’ life after cardiac damage by supporting or restoring heart function, is continuously improving. Common MTE strategies include an engineered ‘vehicle’, which may be a porous scaffold or a dense substrate or patch, made of either natural or synthetic polymeric materials. The function of the substrate is to aid transportation of cells into the diseased region of the heart and support their integration. This book, which contains chapters written by leading experts in MTE, gives a complete analysis of the area and presents the latest advances in the field. The chapters cover all relevant aspects of MTE strategies, including cell sources, specific TE techniques and biomaterials used. Many different cell types have been suggested for cell therapy in the framework of MTE, including autologous bone marrow-derived or cardiac progenitors, as well as embryonic or induced pluripotent stem cells, each having their particular advantages and disadvantages. The book also considers a complete range of biomaterials, examining different aspects of their application in MTE, such as biocompatibility with cardiac cells, mechanical capability and compatibility with the mechanical properties of the native myocardium as well as degradation behaviour in vivo and in vitro. Although a great deal of research is being carried out in the field, this book also addresses many questions that still remain unanswered and highlights those areas in which further research efforts are required. The book will also give an insight into clinical trials and possible novel cell sources for cell therapy in MTE.

Table of contents (11 chapters)

  • Tissue Engineering for Cardiac Regeneration

    Gaetani, Roberto (et al.)

    Pages 1-27

  • Inherently Bio-Active Scaffolds: Intelligent Constructs to Model the Stem Cell Niche

    Nardo, Paolo Di (et al.)

    Pages 29-47

  • Strategies for Myocardial Tissue Engineering: The Beat Goes On

    Akhyari, Payam (et al.)

    Pages 49-79

  • Creating Unique Cell Microenvironments for the Engineering of a Functional Cardiac Patch

    Dvir, Tal (et al.)

    Pages 81-94

  • Intramyocardial Stem Cell Transplantation Without Tissue Engineered Constructs: The Current Clinical Situation

    Donndorf, Peter (et al.)

    Pages 95-110

Buy this book

eBook $149.00
price for USA (gross)
  • ISBN 978-3-642-18056-9
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $199.00
price for USA
  • ISBN 978-3-642-18055-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $199.00
price for USA
  • ISBN 978-3-642-26978-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Rent the ebook  
  • Rental duration: 1 or 6 month
  • low-cost access
  • online reader with highlighting and note-making option
  • can be used across all devices
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Bibliographic Information

Bibliographic Information
Book Title
Myocardial Tissue Engineering
Editors
  • Aldo R. Boccaccini
  • Sian Harding
Series Title
Studies in Mechanobiology, Tissue Engineering and Biomaterials
Series Volume
6
Copyright
2011
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-18056-9
DOI
10.1007/978-3-642-18056-9
Hardcover ISBN
978-3-642-18055-2
Softcover ISBN
978-3-642-26978-3
Series ISSN
1868-2006
Edition Number
1
Number of Pages
X, 270
Topics