Heart Rate and Rhythm

Molecular Basis, Pharmacological Modulation and Clinical Implications

Editors: Tripathi, Onkar N., Ravens, Ursula, Sanguinetti, Michael C. (Eds.)

  • Introduces the molecular and cellular mechanisms that underlie normal and pathophysiological cardiac rhythms
  • Written by experts from various fields
  • Of interest to researchers in cardiac electrophysiology, cell biology, and pharmacology
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eBook $259.00
price for USA (gross)
  • ISBN 978-3-642-17575-6
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $329.00
price for USA
  • ISBN 978-3-642-17574-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $329.00
price for USA
  • ISBN 978-3-642-44579-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Pathological heart rhythms are a major health issue. In this book experts from various fields provide an important context for understanding the complicated molecular and cellular mechanisms that underlie normal and pathophysiological cardiac rhythms. Individual chapters cover a full range of topics, including the ionic basis of pacemaking, the role of specific channels and transporters in sinoatrial node pacemaking, altered intracellular Ca2+ handling in response to disease, computer modeling of the action potentials of pacemaker and working cardiomyocytes, genetic and molecular basis of inherited arrhythmias and a review of established and novel antiarrhythmic agents. Due to the key importance of the specialized pacemaker cells and tissue (sinoatrial and atrioventricular nodes) in maintaining heart rate and rhythm, special emphasis is placed on the peculiar electrophysiology of these cells.

Reviews

From the reviews:

“Heart Rate reigns as one of 2011’s best. Here, physicians are presented with an acute review of how changes in heart rate can be used as a marker to assess patients in the clinical setting. … the writers also extend their treatise to practicing clinicians and ways that the information can be used to better treat patients. Noted for its clear delineation of complex data; with skilled use of illustrations and graphs that re-enforce key points chapter-by-chapter.” (John Aiello, The Electric Review, July, 2011)

Table of contents (37 chapters)

  • Cardiac Ion Channels and Heart Rate and Rhythm

    Tripathi, Onkar Nath

    Pages 3-31

  • Ionic Basis of the Pacemaker Activity of SA Node Revealed by the Lead Potential Analysis

    Himeno, Yukiko (et al.)

    Pages 33-58

  • The “Funny” Pacemaker Current

    Barbuti, Andrea (et al.)

    Pages 59-81

  • Novel Perspectives on Cardiac Pacemaker Regulation: Role of the Coupled Function of Sarcolemmal and Intracellular Proteins

    Maltsev, Victor A. (et al.)

    Pages 83-99

  • Pacemaker Activity of the SA Node: Insights from Dynamic-Clamp Experiments

    Wilders, Ronald (et al.)

    Pages 101-117

Buy this book

eBook $259.00
price for USA (gross)
  • ISBN 978-3-642-17575-6
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $329.00
price for USA
  • ISBN 978-3-642-17574-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $329.00
price for USA
  • ISBN 978-3-642-44579-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Heart Rate and Rhythm
Book Subtitle
Molecular Basis, Pharmacological Modulation and Clinical Implications
Editors
  • Onkar N. Tripathi
  • Ursula Ravens
  • Michael C. Sanguinetti
Copyright
2011
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-17575-6
DOI
10.1007/978-3-642-17575-6
Hardcover ISBN
978-3-642-17574-9
Softcover ISBN
978-3-642-44579-8
Edition Number
1
Number of Pages
XXII, 678
Topics