Epigenetics and Human Health

Brain, Behavior and Epigenetics

Editors: Petronis, Arturas, Mill, Jonathan (Eds.)

  • Epigenetic processes can explain some of the epidemiological associations between environmental exposure and disease, particularly when the exposure occurs at a critical delopmental stage.
  • Epigenetics, a cellular mechanism once considered to be stable after development, has now been found to be a dynamic process that occurs in fully differentiated, post-mitotic cells of central nervous system in response to environmental signals.
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  • ISBN 978-3-642-17426-1
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About this book

Despite significant progress in molecular epigenetic research and its enormous potential, there are still considerable challenges to overcome before we can fully understand the role of epigenetic processes in brain function and behavior. For instance, what comprises a ‘normal’ brain epigenome and what is the degree of region- and cellular-specificity of epigenetic landscapes in the brain? How do the multiple layers of epigenetic information interact and change over time? How common is meiotic epigenetic heritability and what role it may play in complex psychiatric disease? To what extent is the epigenome plastic and malleable in response to environmental influences? This volume demonstrates that such questions can now be explored in an experimental molecular biology laboratory. While the community is only just starting to acknowledge the importance of epigenetic processes in the brain, there is no doubt that numerous breakthrough discoveries in brain and behavioral epigenetics will be made in the decades to come.

Table of contents (14 chapters)

  • Posttranslational Histone Modifications and the Neurobiology of Psychosis

    Akbarian, Schahram (et al.)

    Pages 1-21

  • Epigenetic Regulation of GABAergic Targets in Psychiatry

    Grayson, Dennis R. (et al.)

    Pages 23-40

  • Possible Roles of DNA Methylation in Bipolar Disorder

    Kato, Tadafumi

    Pages 41-47

  • The Epigenetics of Depression and Suicide

    Labonté, Benoit (et al.)

    Pages 49-70

  • Epidemiology Research and Epigenetics: Translational Epidemiology of Schizophrenia

    Perrin, Mary (et al.)

    Pages 71-96

Buy this book

eBook $219.00
price for USA (gross)
  • ISBN 978-3-642-17426-1
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $279.00
price for USA
  • ISBN 978-3-642-17425-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $279.00
price for USA
  • ISBN 978-3-642-26832-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Brain, Behavior and Epigenetics
Editors
  • Arturas Petronis
  • Jonathan Mill
Series Title
Epigenetics and Human Health
Copyright
2011
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-17426-1
DOI
10.1007/978-3-642-17426-1
Hardcover ISBN
978-3-642-17425-4
Softcover ISBN
978-3-642-26832-8
Series ISSN
2191-2262
Edition Number
1
Number of Pages
XVI, 320
Topics