Biology of Extracellular Matrix

Extracellular Matrix Degradation

Editors: Parks, William C., Mecham, Robert (Eds.)

  • Provides timely reviews on current topics of extracellular matrix (ECM)  biology
  • Improves understanding of the role of matrix-degrading proteases in tissue remodeling and diseases
  • Published in collaboration with the American Society for Matrix Biology
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eBook $179.00
price for USA (gross)
  • ISBN 978-3-642-16861-1
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  • Immediate eBook download after purchase
Hardcover $229.00
price for USA
  • ISBN 978-3-642-16860-4
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  • Usually dispatched within 3 to 5 business days.
Softcover $229.00
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  • ISBN 978-3-642-26780-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Regulated turnover of extracellular matrix (ECM) is an important component of tissue homeostasis. In recent years, the enzymes that participate in, and control ECM turnover have been the focus of research that touches on development, tissue remodeling, inflammation and disease. This volume in the Biology of Extracellular Matrix series provides a review of the known classes of proteases that degrade ECM both outside and inside the cell. The specific EMC proteases that are discussed include cathepsins, bacterial collagenases, matrix metalloproteinases, meprins, serine proteases, and elastases. The volume also discusses the domains responsible for specific biochemical characteristics of the proteases and the physical interactions that occur when the protease interacts with substrate. The topics covered in this volume provide an important context for understanding the role that matrix-degrading proteases play in normal tissue remodeling and in diseases such as cancer and lung disease.

The series Biology of Extracellular Matrix is published in collaboration with the American Society for Matrix Biology.

Table of contents (9 chapters)

  • Matrix Metalloproteinases and Their Inhibitors in Turnover and Degradation of Extracellular Matrix

    Gill, Sean E. (et al.)

    Pages 1-22

  • Role of Cysteine Cathepsins in Extracellular Proteolysis

    Brömme, Dieter (et al.)

    Pages 23-51

  • Cooperation Between Proteolysis and Endocytosis in Collagen Turnover

    Bugge, Thomas H. (et al.)

    Pages 53-74

  • Pericellular Proteolysis

    Bond, Judith S. (et al.)

    Pages 75-94

  • Triple Helicase Activity and the Structural Basis of Collagenolysis

    Nagase, Hideaki (et al.)

    Pages 95-122

Buy this book

eBook $179.00
price for USA (gross)
  • ISBN 978-3-642-16861-1
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $229.00
price for USA
  • ISBN 978-3-642-16860-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $229.00
price for USA
  • ISBN 978-3-642-26780-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Extracellular Matrix Degradation
Editors
  • William C. Parks
  • Robert Mecham
Series Title
Biology of Extracellular Matrix
Copyright
2011
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-16861-1
DOI
10.1007/978-3-642-16861-1
Hardcover ISBN
978-3-642-16860-4
Softcover ISBN
978-3-642-26780-2
Series ISSN
0887-3224
Edition Number
1
Number of Pages
X, 255
Topics