Epigenetics and Human Health

Epigenetics and Human Reproduction

Editors: Rousseaux, Sophie, Khochbin, Saadi (Eds.)

  • Epigenetics is a rapidly expanding field in medical and biological research which concerns heritable traits that are not attributable to changes in the DNA sequence
  • Epigenetic mechanisms play key roles in many biological processes, and it has become clear that their disruption can gives rise to diverse pathologies in humans
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eBook $229.00
price for USA (gross)
  • ISBN 978-3-642-14773-9
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $289.00
price for USA
  • ISBN 978-3-642-14772-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $289.00
price for USA
  • ISBN 978-3-642-26582-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Epigenetics is a rapidly expanding field in medical and biological research which concerns heritable traits that are not attributable to changes in the DNA sequence. Epigenetic mechanisms play key roles in many biological processes, and it has become clear that their disruption can gives rise to diverse pathologies in humans. Edited by preeminent experts, Sophie Rousseaux and Saadi Khochbin, this volume in the ‘Epigenetics and Human Health’ series discusses the role of epigenetics in human reproduction. The book presents epigenetic transitions that are important at defined stages of gametogenesis and during meiosis. Several of the sixteen chapters written by experts in the field cover fundamental concepts discovered through cellular and biochemical work and from research on animal models. In other chapters, key examples are provided of how disruption of these mechanisms affects germ cell development and fertility, and contributes to the germinal cancers. Finally, the book discusses how in vitro manipulation and culture in assisted reproduction can epigenetically perturb germ cells, and how this can trigger disease phenotypes in the next generation. Conceived towards advanced students, medical professionals and research scientists, this is the first comprehensive textbook on this topic that will serve as a valuable reference during the years to come

Table of contents (15 chapters)

  • Potential Epigenetic Consequences Associated with Assisted Reproduction

    Fortier, Amanda (et al.)

    Pages 3-18

  • Germ Cell Cancer, Testicular Dysgenesis Syndrome and Epigenetics

    Almstrup, Kristian (et al.)

    Pages 19-44

  • Medical Implications of Sperm Nuclear Quality

    Oliva, Rafael (et al.)

    Pages 45-83

  • Gene Expression/Phenotypic Abnormalities in Placental Tissues of Sheep Clones: Insurmountable Block in Cloning Progress?

    Loi, Pasqualino (et al.)

    Pages 85-96

  • Epigenetic Reprogramming Associated with Primordial Germ Cell Development

    Seki, Yoshiyuki

    Pages 99-117

Buy this book

eBook $229.00
price for USA (gross)
  • ISBN 978-3-642-14773-9
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $289.00
price for USA
  • ISBN 978-3-642-14772-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $289.00
price for USA
  • ISBN 978-3-642-26582-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Epigenetics and Human Reproduction
Editors
  • Sophie Rousseaux
  • Saadi Khochbin
Series Title
Epigenetics and Human Health
Copyright
2011
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-14773-9
DOI
10.1007/978-3-642-14773-9
Hardcover ISBN
978-3-642-14772-2
Softcover ISBN
978-3-642-26582-2
Series ISSN
2191-2262
Edition Number
1
Number of Pages
XVI, 372
Topics