Results and Problems in Cell Differentiation

Sensory and Metabolic Control of Energy Balance

Editors: Meyerhof, Wolfgang, Beisiegel, Ulrike, Joost, Hans-Georg (Eds.)

  • Up-to-date account of the scientific progress made in the understanding of molecular mechanisms regulating energy metabolism
  • Special emphasis on obesity
  • Written by experts in the field
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eBook $229.00
price for USA (gross)
  • ISBN 978-3-642-14426-4
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Hardcover $299.00
price for USA
  • ISBN 978-3-642-14425-7
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  • Usually dispatched within 3 to 5 business days.
Softcover $299.00
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  • ISBN 978-3-642-26518-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

The prevalence of obesity has dramatically increased in western and westernized societies, making the disease the second leading cause of unnecessary deaths in the US. Obesity results from imbalanced metabolic regulation leading to excessive lipid storage. As important novel entities in metabolic regulation, taste receptors and their cells are critical elements that adapt the gustatory system to metabolic signals and vice versa. The role of taste receptor genes in gastrointestinal tissues, as well as their dynamic regulation in gustatory and non-gustatory tissues in response to metabolic cues, has become the focus of an entirely new and rapidly developing research field with impacts on fuel sensing, metabolic control, and ingestive behavior. This book reflects the recent scientific progress in the field of fuel sensing in the mouth, GI tract, and brain and examines the olfactory bulb as a potential metabolic sensor and the brain-gut endocrine axis. It also touches on relevant novel molecular and cellular mechanisms regulating lipid storage and metabolism and covers the identification and functional characterization of obesity genes. Lastly, it illustrates the use of insect models to study relevant problems of energy homeostasis.

Table of contents (16 chapters)

  • The Genetic Basis of Obesity and Type 2 Diabetes: Lessons from the New Zealand Obese Mouse, a Polygenic Model of the Metabolic Syndrome

    Joost, Hans-Georg

    Pages 1-11

  • Regulation of Nutrient Metabolism and Inflammation

    Kersten, Sander

    Pages 13-25

  • Lipid Storage in Large and Small Rat Adipocytes by Vesicle-Associated Glycosylphosphatidylinositol-Anchored Proteins

    Müller, Günter (et al.)

    Pages 27-34

  • Autophagy and Regulation of Lipid Metabolism

    Singh, Rajat

    Pages 35-46

  • Gene Co-Expression Modules and Type 2 Diabetes

    Attie, Alan D. (et al.)

    Pages 47-56

Buy this book

eBook $229.00
price for USA (gross)
  • ISBN 978-3-642-14426-4
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $299.00
price for USA
  • ISBN 978-3-642-14425-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $299.00
price for USA
  • ISBN 978-3-642-26518-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Sensory and Metabolic Control of Energy Balance
Editors
  • Wolfgang Meyerhof
  • Ulrike Beisiegel
  • Hans-Georg Joost
Series Title
Results and Problems in Cell Differentiation
Series Volume
52
Copyright
2010
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-14426-4
DOI
10.1007/978-3-642-14426-4
Hardcover ISBN
978-3-642-14425-7
Softcover ISBN
978-3-642-26518-1
Series ISSN
0080-1844
Edition Number
1
Number of Pages
VIII, 208
Number of Illustrations and Tables
12 b/w illustrations, 30 illustrations in colour
Topics