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  • © 2010

Biomaterials as Stem Cell Niche

Editors:

  • Provides the state-of-the-art developments in using biomaterials as artificial niches for engineering stem cells
  • Gives a better understanding stem cell biology under 3D biomimetic conditions
  • Includes supplementary material: sn.pub/extras

Part of the book series: Studies in Mechanobiology, Tissue Engineering and Biomaterials (SMTEB, volume 2)

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Table of contents (12 chapters)

  1. Front Matter

    Pages i-viii
  2. Engineering ECM Complexity into Biomaterials for Directing Cell Fate

    • Sarah E. Stabenfeldt, Ashley Carson Brown, Thomas H. Barker
    Pages 1-18
  3. Functional Biomaterials for Controlling Stem Cell Differentiation

    • Ameya Phadke, Chien-Wen Chang, Shyni Varghese
    Pages 19-44
  4. Integration of Biomaterials into 3D Stem Cell Microenvironments

    • Andres Bratt-Leal, Richard Carpenedo, Todd McDevitt
    Pages 45-59
  5. Stem Cell Interaction with Topography

    • Benjamin K. K. Teo, Soneela Ankam, Evelyn K. F. Yim
    Pages 61-87
  6. The Nanofiber Matrix as an Artificial Stem Cell Niche

    • Hai-Quan Mao, Shawn H. Lim, Shuming Zhang, Gregory Christopherson, Korey Kam, Stephen Fischer
    Pages 89-118
  7. Micropatterned Hydrogels for Stem Cell Culture

    • Sharon K. Hamilton, Hang Lu, Johnna S. Temenoff
    Pages 119-152
  8. Microengineering Approach for Directing Embryonic Stem Cell Differentiation

    • Hojae Bae, Jason W. Nichol, Amir Foudeh, Behnam Zamanian, Cheong Hoon Kwon, Ali Khademhosseini
    Pages 153-171
  9. Biomaterials as Stem Cell Niche: Cardiovascular Stem Cells

    • Ge Zhang, Laura J. Suggs
    Pages 173-193
  10. The Integrated Role of Biomaterials and Stem Cells in Vascular Regeneration

    • Guoming Sun, Sravanti Kusuma, Sharon Gerecht
    Pages 195-223
  11. Synthetic Niches for Stem Cell Differentiation into T cells

    • Ankur Singh, Krishnendu Roy
    Pages 225-245
  12. Back Matter

    Pages 309-309

About this book

Recent developments in stem cell biology have opened new directions in cell therapy. This book provides the state-of-the-art developments in using biomaterials as artificial niches for engineering stem cells, both for the purpose of better understanding their biology under 3D biomimetic conditions as well as for developing new strategies for efficient long term maintenance and directed differentiation of stem cells into various therapeutic lineages. Animal and human stem cells of both embryonic and adult origin are discussed with applications ranging from nerve regeneration, orthopedics, cardiovascular therapy, blood cell generation and cancer therapy. Both synthetic and natural biomaterials are reviewed with emphasis on how material-stem cell interactions direct specific signaling pathways and ultimately modulate the cell fate. This book is valuable for biomaterial scientists, tissue engineers, clinicians as well as stem cell biologists involved in basic research and applications of adult and embryonic stem cells.

Editors and Affiliations

  • Cockrell School of Engineering, Dept. Biomedical Engineering, University of Texas, Austin, Austin, USA

    Krishnendu Roy

Bibliographic Information

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access