Heterocyclic Scaffolds I

1. Front Matter

   Pages i-xi

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2. Novel Aspects on the Preparation of Spirocyclic and Fused Unusual β-Lactams

   • Benito Alcaide, Pedro Almendros

   Pages 1-48

3. Spirocyclic β-Lactams: Synthesis and Biological Evaluation of Novel Heterocycles

   • Shamsher S. Bari, Aman Bhalla

   Pages 49-99

4. Novel and Recent Synthesis and Applications of β-Lactams

   • Luigino Troisi, Catia Granito, Emanuela Pindinelli

   Pages 101-209

5. β-Lactam Ring Opening: A Useful Entry to Amino Acids and Relevant Nitrogen-Containing Compounds

   • C. Palomo, M. Oiarbide

   Pages 211-259

6. Recent Approaches Toward Solid Phase Synthesis of β-Lactams

   • Bablee Mandal, Pranab Ghosh, Basudeb Basu

   Pages 261-311

7. Computational Studies on the Synthesis of β-Lactams via [2+2] Thermal Cycloadditions

   • Ana Arrieta, Begoña Lecea, Fernando P. Cossío

   Pages 313-347

8. Novel Anticancer β-Lactams

   • Bimal K. Banik, Indrani Banik, Frederick F. Becker

   Pages 349-373

9. Back Matter

   Pages 375-379

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Contents: B. Alcaide ∙ P. Almendros: Novel Aspects on the Preparation of Spirocyclic and Fused Unsual β-Lactams.- S.S. Bari ∙ A. Bhalla: Spirocyclic β-Lactams: Synthesis and Biological Evaluation of Novel Heterocycles.- L. Troisi ∙ C. Granito ∙ E. Pindinelli: Novel and Recent Synthesis and Applications of β-Lactams.- C. Palomo ∙ M. Oiarbide: β-Lactams Ring Opening: A Useful Entry to Amino Acids and Relevant Nitrogen-Containing Compounds.- B. Mandal ∙ P. Ghosh ∙ B. Basu: Recent Approaches Towards Solid Phase Synthesis of β-Lactams.- A.Arrieta ∙ B. Lecea ∙ F.P. Cossio: Computational Studies on the Synthesis of β-Lactams Via [ 2+2] Thermal Cycloadditions.- B. K. Banik ∙ I. Banik ∙ F. F. Becker: Novel Anticancer β-Lactams

• Cycloaddition
• cholesterol-lowering drugs
• heterocycles, nitrogen-containing
• inhibitors of ß-lactamases
• synthesis, stereocontrolled
• ß-lactam antibiotics
• ß-lactam anticancer agents

From the reviews:

“This monograph on the ß-lactam scaffold, the latest in the Topics in Heterocyclic Chemistry series, does an admirable job of covering recent developments. … Overall, this volume constitutes a systematic, thorough, and densely packed compendium of recent synthetic developments in the ß-lactam area and should be of use to anyone wishing to pursue research in this field. The individual chapters are organized, thorough, and up to date, with most including references up to 2008.” (John D. Buynak, Journal of the American Chemical Society, Vol. 133, 2011)

• Dept. Chemistry, University of Texas-Pan American, Edinburg, USA

  Bimal K. Banik

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