Overview
- Includes supplementary material: sn.pub/extras
Part of the book series: Research and Perspectives in Endocrine Interactions (RPEI)
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Table of contents (13 papers)
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Front Matter
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Back Matter
Keywords
About this book
We are now on the verge of viewing effector molecules and other regulatory sites as therapeutic targets for the amelioration of human and animal disease. The recognition, for example, that mutant proteins are frequently misrouted molecules, rather than functionally defective ones, changes our approach to "inborn errors of metabolism" and offers new approaches for pharmacological discovery, based on rescue of receptors, ion channels and enzymes with pharmacoperones. Ion channels, regulators of G-protein signaling and enzymes engaged in regulation, now present opportunities for drug development.
The state of our art also benefits by the availability of superior tools that allow measurement of interactions and afford unprecedented insight into the biomolecular interactions that present novel approaches to drug design.
Editors and Affiliations
Bibliographic Information
Book Title: Insights into Receptor Function and New Drug Development Targets
Editors: Michael Conn, Claude Kordon, Yves Christen
Series Title: Research and Perspectives in Endocrine Interactions
DOI: https://doi.org/10.1007/3-540-34447-0
Publisher: Springer Berlin, Heidelberg
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer-Verlag Berlin Heidelberg 2006
Hardcover ISBN: 978-3-540-34446-9Published: 25 July 2006
Softcover ISBN: 978-3-642-07080-8Published: 22 November 2010
eBook ISBN: 978-3-540-34447-6Published: 28 September 2006
Series ISSN: 1861-2253
Series E-ISSN: 1863-0685
Edition Number: 1
Number of Pages: XV, 202
Topics: Pharmacology/Toxicology, Biomedicine general, Endocrinology