Advances in Anatomy, Embryology and Cell Biology

Morphological and Cellular Aspects of Tail and Limb Regeneration in Lizards

A Model System With Implications for Tissue Regeneration in Mammals

Authors: Alibardi, Lorenzo

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  • ISBN 978-3-642-03733-7
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Softcover $189.00
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About this book

The present review deals with the analysis of the cytological processess occurring during tissue regeneration in the tail and limb of lizards. These reptiles are considered as a model to understand the process of tissue regeneration in all amniotes. The review begins with some evolutive considerations on the origin of tail regeneration in comparison to the failure of limb regeneration, a unique case among amniotes. The formation of the tail in the embryo and the possible accumulation of stem cells in autotomous planes of the tail are discussed. The histological and ultrastructural processess occuring during blastema formation and tail regeneration and during limb cicatrization are presented. The comparison stresses the scarse to absent inflammatory reaction present in the tail vs the massive inflammatory response in the limb leading to scarring. In fact the experimental induction of a strong inflammation in the tail also leads to scarring. The importance of the nervous system in stimulating tail regeneration in lizards is emphasized. The presence of growth factors and extracellular matrix proteins during wound healing of the tail and limb is introduced. The review concludes stressing the importance of the lizard model of tissue regeneration for medical studies and applications.

Reviews

From the book reviews:

“This is an exploration into the controversies about amphibian/mammalian limb regeneration. … I recommend this book for developmental biologists, orthopaedic surgeons, students, and fellows with interests in the molecular, cellular, and tissue aspects of regeneration.” (Joseph J. Grenier, Amazon.com, August, 2014)


Table of contents (4 chapters)

  • Regeneration in Reptiles and Its Position Among Vertebrates

    Alibardi, Lorenzo

    Pages 1-49

  • Tail Regeneration: Ultrastructural and Cytological Aspects

    Alibardi, Lorenzo

    Pages 51-88

  • Limb Regeneration: Ultrastructural and Cytological Aspects

    Alibardi, Lorenzo

    Pages 89-93

  • Conclusion and Perspectives: Implications for Human Regeneration

    Alibardi, Lorenzo

    Pages 95-97

Buy this book

eBook $149.00
price for USA (gross)
  • ISBN 978-3-642-03733-7
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $189.00
price for USA
  • ISBN 978-3-642-03732-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Morphological and Cellular Aspects of Tail and Limb Regeneration in Lizards
Book Subtitle
A Model System With Implications for Tissue Regeneration in Mammals
Authors
Series Title
Advances in Anatomy, Embryology and Cell Biology
Series Volume
207
Copyright
2010
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-03733-7
DOI
10.1007/978-3-642-03733-7
Softcover ISBN
978-3-642-03732-0
Series ISSN
0301-5556
Edition Number
1
Number of Pages
XII, 112
Number of Illustrations and Tables
20 b/w illustrations, 8 illustrations in colour
Topics