Genome Dynamics and Stability

Transposons and the Dynamic Genome

Editors: Lankenau, Dirk, Volff, Jean-Nicolas (Eds.)

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About this book

There are only few major key functions that lie beneath the fundamental architecture of metabolism and life. These are multiplication, variation and heredity. Only if these factors interact synergistically can Darwinian selection power the evolution of biodiversity. Transposable elements have always played a major role in this process. The genomes of all organisms consist of chromosomes that are built up of double-stranded nucleic acid chains on whose stability and integrity the existence of cells depend. While DNA repair warrants the chemical integrity of DNA and protects it from metabolic and environmental mutagens, meiotic recombination and transposable element activity appear to counteract the molecular guardians of genome stability. Transposable elements and their kind often make up the bulk of genomic DNA, often approaching 50% of the genome. By contrast, the classic genes represent as little as 1.8% of genomic DNA, in case of the human genome.

This volume gives an overview on mobile DNA and how such contradiction to the obligatory stability of genomes can be understood. Obviously, an understanding can only be achieved by cutting deeply into the evolutionary history of life along with the evolution of transposable elements and dynamic genomes.

This book therefore also celebrates Charles Darwin’s 200th birthday. The reader is challenged to view the role of movable DNA along historical roots from the levels of cells to populations to biological species integrating the accompanying molecular evolution of host, cell and genome interaction. One will witness even the reactivation of a long since dead, fossil transposable element and the infection of germline cells by the first established, mobile and endogenous insect retrovirus.

Table of contents (7 chapters)

  • Theoretical Approaches to the Dynamics of Transposable Elements in Genomes, Populations, and Species

    Le Rouzic, Arnaud (et al.)

    Pages 1-19

  • Infra- and Transspecific Clues to Understanding the Dynamics of Transposable Elements

    Vieira, Cristina (et al.)

    Pages 21-43

  • Morphological Characters from the Genome: SINE Insertion Polymorphism and Phylogenies

    Dettaï, Agnès (et al.)

    Pages 45-75

  • Genome Defense Against Transposable Elements and the Origins of Regulatory RNA

    Jordan, I. King (et al.)

    Pages 77-94

  • When Drosophila Meets Retrovirology: The gypsy Case

    Terzian, Christophe (et al.)

    Pages 95-107

Buy this book

eBook $229.00
price for USA (gross)
  • ISBN 978-3-642-02005-6
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $299.00
price for USA
  • ISBN 978-3-642-02004-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $299.00
price for USA
  • ISBN 978-3-642-24252-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Transposons and the Dynamic Genome
Editors
  • Dirk Lankenau
  • Jean-Nicolas Volff
Series Title
Genome Dynamics and Stability
Series Volume
4
Copyright
2009
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-02005-6
DOI
10.1007/978-3-642-02005-6
Hardcover ISBN
978-3-642-02004-9
Softcover ISBN
978-3-642-24252-6
Series ISSN
1861-3373
Edition Number
1
Number of Pages
XV, 184
Topics