Topics in Medicinal Chemistry

Ion Channels

Editors: Fermini, Bernard, Priest, Birgit (Eds.)

  • Includes an overview chapter that introduces the newcomer to the topic
  • Part of a series that covers hot topics of frontier research summarized by reputed scientists in the field
  • Review series is topic related
  • Online version available on SpringerLink: springerlink.com
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eBook $289.00
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  • ISBN 978-3-540-79729-6
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Hardcover $369.00
price for USA
  • ISBN 978-3-540-79728-9
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  • Usually dispatched within 3 to 5 business days.
Softcover $369.00
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  • ISBN 978-3-642-09855-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Ion channels play a vital role in basic physiological functions such as generation of electrical activity in nerves and muscle, control of cardiac excitability, intracellular signaling, hormone secretion, cell proliferation and many other biological processes. Because of their prevalence and the critical role they play in virtually all tissue types and organs, ion channels are also involved in a number of pathophysiological conditions. The aim of this volume is to review recent advances in the field of ion channel related diseases. Following an overview chapter summarizing the current state of ion channel screening technologies, five topics covering areas such as cancer, cardiac arrhythmias, cystic fibrosis, and pain have been selected, and the current state of knowledge is presented by leading experts in their field. Each chapter is structured to cover the biological rationale for the target, the current status in the development of agents to treat the disease, and future prospects and challenges facing each therapeutic area. The reader will receive a critical overview covering the progress made in the rapidly developing and complex field of ion channels and diseases.

Table of contents (6 chapters)

  • Recent Advances in Ion Channel Screening Technologies

    Fermini, Bernard

    Pages 1-25

  • Role of Kv7 and Cav3 Ion Channels in Pain

    Krafte, Douglas S. (et al.)

    Pages 27-54

  • Potassium Channels: Oncogenic Potential and Therapeutic Target for Cancers

    Wang, Zhiguo

    Pages 55-89

  • Pharmacological Rescue of Mutant CFTR Function for the Treatment of Cystic Fibrosis

    Goor, Fredrick (et al.)

    Pages 91-120

  • On the Process of Finding Novel and Selective Sodium Channel Blockers for the Treatment of Diseases

    Priest, Birgit T.

    Pages 121-143

Buy this book

eBook $289.00
price for USA (gross)
  • ISBN 978-3-540-79729-6
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $369.00
price for USA
  • ISBN 978-3-540-79728-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $369.00
price for USA
  • ISBN 978-3-642-09855-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Ion Channels
Editors
  • Bernard Fermini
  • Birgit Priest
Series Title
Topics in Medicinal Chemistry
Series Volume
3
Copyright
2008
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-540-79729-6
DOI
10.1007/978-3-540-79729-6
Hardcover ISBN
978-3-540-79728-9
Softcover ISBN
978-3-642-09855-0
Series ISSN
1862-2461
Edition Number
1
Number of Pages
XIV, 171
Number of Illustrations and Tables
33 b/w illustrations, 10 illustrations in colour
Topics