Overview
- Discusses the mechanisms underlying the function of SAPKs and the relevance of these signalling pathways in different organisms
- Written by international experts
- Includes supplementary material: sn.pub/extras
Part of the book series: Topics in Current Genetics (TCG, volume 20)
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Table of contents (17 chapters)
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Front Matter
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Back Matter
Keywords
About this book
To maximize the probability of survival, cells need to coordinate their intracellular activities in response to changes in the extracellular environment. MAP kinase cascades play an important role in the transduction of signals inside eukaryotic cells. In particular, stress stimuli result in the rapid activation of a highly conserved group of MAP kinases, known as SAPKs (Stress-Activated Protein Kinases). These kinases coordinate the generation of adaptive responses that are essential for cell survival, which include the modulation of several aspects of cell physiology from metabolism to gene expression.
In this book, leading researchers in the field discuss the state-of-the-art of many aspects of SAPK signalling in various systems from yeast to mammals. These include various chapters on regulatory mechanisms as well as the contribution of the SAPK signalling pathways to processes such as gene expression, metabolism, cell cycle regulation, immune responses and tumorigenesis.
Bibliographic Information
Book Title: Stress-Activated Protein Kinases
Editors: Francesc Posas, Angel R. Nebreda
Series Title: Topics in Current Genetics
DOI: https://doi.org/10.1007/978-3-540-75569-2
Publisher: Springer Berlin, Heidelberg
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer-Verlag Berlin Heidelberg 2008
Hardcover ISBN: 978-3-540-75568-5Published: 10 January 2008
Softcover ISBN: 978-3-642-09480-4Published: 23 November 2010
eBook ISBN: 978-3-540-75569-2Published: 24 January 2008
Series ISSN: 1610-2096
Series E-ISSN: 1610-6970
Edition Number: 1
Number of Pages: XVIII, 314
Topics: Biochemistry, general, Cell Biology, Molecular Medicine