Topics in Current Genetics

Metabolomics

A Powerful Tool in Systems Biology

Editors: Nielsen, Jens, Jewett, Michael C. (Eds.)

  • Addresses all major challenges of the field
  • Offers real strategies for understanding cellular complexity
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eBook $259.00
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  • ISBN 978-3-540-74719-2
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Hardcover $329.00
price for USA
  • ISBN 978-3-540-74718-5
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  • Usually dispatched within 3 to 5 business days.
Softcover $329.00
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  • ISBN 978-3-642-09418-7
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About this book

The metabolome comprises the complete set of metabolites, the non-genetically encoded substrates, intermediates, and products of metabolic pathways, associated to a cell. Given the increasing demand to quantitatively identify the metabolome and understand how trafficking of metabolites through the metabolic network impact cellular behavior, metabolomics has emerged as an important complementary technology to the cell-wide measurements of mRNA, proteins, fluxes, and interactions (e.g. protein-DNA). Metabolomics is already a powerful tool in drug discovery and development and in metabolic engineering. While maintaining these strengths, the field promises to play a heightened role in systems biology research, which is transforming the practice of medicine and our ability to engineer living organisms.

This book brings together the latest results in the field of metabolomics. It comprehensively presents the current state of the metabolomics field by underscoring experimental methods, analysis techniques, standardization practices, and advances in specific model systems. As a result, it significantly broadens our perspective on the principles and strategies underpinning this emerging field.

Table of contents (10 chapters)

  • The role of metabolomics in systems biology

    Nielsen, Jens (et al.)

    Pages 1-10

  • Analytical methods from the perspective of method standardization

    Villas-Bôas, Silas G. (et al.)

    Pages 11-52

  • Reporting standards

    Hardy, Nigel (et al.)

    Pages 53-73

  • The Golm Metabolome Database: a database for GC-MS based metabolite profiling

    Hummel, Jan (et al.)

    Pages 75-95

  • Reconstruction of dynamic network models from metabolite measurements

    Reuss, Matthias (et al.)

    Pages 97-127

Buy this book

eBook $259.00
price for USA (gross)
  • ISBN 978-3-540-74719-2
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $329.00
price for USA
  • ISBN 978-3-540-74718-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $329.00
price for USA
  • ISBN 978-3-642-09418-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Metabolomics
Book Subtitle
A Powerful Tool in Systems Biology
Editors
  • Jens Nielsen
  • Michael C. Jewett
Series Title
Topics in Current Genetics
Series Volume
18
Copyright
2007
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-540-74719-2
DOI
10.1007/978-3-540-74719-2
Hardcover ISBN
978-3-540-74718-5
Softcover ISBN
978-3-642-09418-7
Series ISSN
1610-2096
Edition Number
1
Number of Pages
XVI, 284
Number of Illustrations and Tables
40 b/w illustrations, 13 illustrations in colour
Topics