Radiation Oncology

The Impact of Tumor Biology on Cancer Treatment and Multidisciplinary Strategies

Editors: Molls, M., Vaupel, P., Nieder, C., Anscher, M.S. (Eds.)

  • Provides a detailed overview of the fundamentals of tumor biology and the influence of various biologic factors on the design of therapeutic strategies and the outcome of established and emerging treatments
  • Particular attention is devoted to multidisciplinary combined modality therapy
  • All of the chapters have been written by experienced basic scientists, clinical researchers, and cancer professionals
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eBook $219.00
price for USA (gross)
  • ISBN 978-3-540-74386-6
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $279.00
price for USA
  • ISBN 978-3-540-74385-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $279.00
price for USA
  • ISBN 978-3-642-09382-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This book provides an overview of the fundamentals of tumor biology and the influence of various biologic factors, including inhomogeneity of cancer cells, microenvironment, and host factors, on the design of therapeutic strategies and the outcome of established and emerging treatments. Particular attention is devoted to multidisciplinary combined modality therapy. The topics reviewed include tumorigenesis, cell proliferation, angiogenesis, physiology of malignant tissues, adhesion and invasion, development of metastases, and the role of the immune system in cancer development. Subsequent chapters focus on cancer prevention, detection, and treatment. The principles of chemotherapy, radiotherapy, and molecularly targeted therapy are discussed, treatment resistance is explained, and strategies for rational combinations are provided, including the design of translational studies. Furthermore, the principles and clinical implications of new diagnostic and therapeutic approaches, such as gene expression profiling, gene transfer and silencing, proteomics, and molecular imaging, are presented. The chapters in this book have been written by an outstanding group of basic scientists, clinical researchers, and cancer professionals with long experience in the field. Their aim is to educate and inspire all those who devote most of their work to research into cancer and its treatment.

About the authors

M. Molls, Professor, Chairman of the Department of Radiation Oncology, Klinikum rechts der Isar der TU Muenchen, Germany

C. Nieder, Professor at the University of Tromsø, Norway, Oncologist

M Anscher, Professor and Chairman, Department of Radiation Oncology, Virginia Commonwealth University School of Medicine, Richmond, Virginia, USA

Reviews

From the reviews: “The stated aim of the editors of this book is ‘to provide the practising radiation oncologist with a concise overview of the most important and up-to-date information pertaining to tumour biology as it impacts on cancer treatment’ … useful guide to the molecular era of cancer biology and personalised cancer therapy, particularly in relation to radiation oncology. … The book would be of interest to any oncologist and would serve as a useful revision tool for the FRCR part 1 examination.” (Joe O’Sullivan, RAD Magazine, December, 2009) Aus den Rezensionen: “Dieses umfassende Lehrbuch erläutert alle wesentlichen Gesichtspunkte der Tumorbiologie ... Die Literaturhinweise sind umfangreich, vollständig und aktuell, sofern dies in einem Lehrbuch überhaupt möglich ist. Die Autoren sind international ausgewiesene Grundlagenwissenschaftler und klinische Krebsforscher. Die Kapitel weisen ein qualitativ hochwertiges Layout mit zahlreichen, durchgehend farbigen Bildern auf und sind gut lesbar. Das Buch stellt eine wesentliche Bereicherung der tumorbiologischen Literatur dar. Wir empfehlen es als aktuelles radiobiologisches Standardwerk.“ (Stephan Roth, in: Strahlentherapie und Onkologie, 1/December/2009, S. 844)

Table of contents (21 chapters)

  • Tumorigenesis

    Atkinson, Michael J. (et al.)

    Pages 1-17

  • Tumor Growth and Cell Proliferation

    Los, Marek (et al.)

    Pages 19-37

  • Tumor Angiogenesis

    Schneider, Vesile (et al.)

    Pages 39-50

  • Pathophysiology of Solid Tumors

    Vaupel, Peter

    Pages 51-92

  • Adhesion, Invasion, Integrins, and Beyond

    Cordes, Nils (et al.)

    Pages 93-115

Buy this book

eBook $219.00
price for USA (gross)
  • ISBN 978-3-540-74386-6
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $279.00
price for USA
  • ISBN 978-3-540-74385-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $279.00
price for USA
  • ISBN 978-3-642-09382-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
The Impact of Tumor Biology on Cancer Treatment and Multidisciplinary Strategies
Editors
  • Michael Molls
  • Peter Vaupel
  • Carsten Nieder
  • Mitchell Steven Anscher
Series Title
Radiation Oncology
Copyright
2009
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-540-74386-6
DOI
10.1007/978-3-540-74386-6
Hardcover ISBN
978-3-540-74385-9
Softcover ISBN
978-3-642-09382-1
Edition Number
1
Number of Pages
X, 367
Topics