Overview
- Editors:
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R. Rigler
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Laboratory of Medical Biophysics, MBB, Karolinska Institute, Stockolm, Sweden
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H. Vogel
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Laboratory of Physical Chemistry of Polymers and Membranes Institute of Chemical Sciences and Engineering, Swiss Federal Institute of Technology (EPFL), Lausanne, Switzerland
- Comprehensive overview on the fast developing field of single molecule detection
- Written by experts in the field
- Includes supplementary material: sn.pub/extras
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Table of contents (11 chapters)
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Front Matter
Pages i-xiii
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- W. E. Moerner, P. James Schuck, David P. Fromm, Anika Kinkhabwala, Samuel J. Lord, Stefanie Y. Nishimura et al.
Pages 1-23
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- Clemens Hofmann, Florian Kulzer, Rob Zondervan, Jürgen Köhler, Michel Orrit
Pages 25-51
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- Laurent A. Bentolila, Xavier Michalet, Shimon Weiss
Pages 53-81
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- Zdeněk Petrášek, Petra Schwille
Pages 83-105
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- Sandra De Keijzer, B. Ewa Snaar-Jagalska, Herman P. Spaink, Thomas Schmidt
Pages 107-129
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- Michael Prummer, Horst Vogel
Pages 131-162
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- Wendy Verheijen, Davey Loos, Frans C. De Schryver, Johan Hofkens
Pages 163-180
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- Benjamin Schuler, Gilad Haran
Pages 181-215
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- Aldo Jesorka, Michal Tokarz, Owe Orwar
Pages 217-250
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- Hagan Bayley, Tudor Luchian, Seong-Ho Shin, Mackay B. Steffensen
Pages 251-277
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- Andreas Engel, Harald Janovjak, Dimtrios Fotiadis, Alexej Kedrov, David Cisneros, Daniel J. Müller
Pages 279-311
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Back Matter
Pages 313-318
About this book
The investigation of molecules as individuals has grown rapidly in recent years, and in the process has uncovered molecular properties not normally accessible by ensemble experiments. In particular, the direct characterization of biologically important molecules such as enzymes, molecular motors, or receptors and entire signaling complexes in action, for example in a live biological cell, yielded un- pected insights. Common approaches for studying single molecules include the electrical detection of ion channels in membranes, the measurement of the dynamics of (bio)chemical reactions between individual molecules, the imaging of individual molecules by scanning probe techniques or by fluorescence correlation spectr- copy, and the direct monitoring of single molecules by optical microscopies, to mention a few. The application of these techniques in physics, chemistry, and bi- ogy has opened new areas of nanotechnology. This book provides a representative selection of recent developments in the rapidly evolving field of single molecule techniques of importance in life sciences and will have future impact on the quan- tative description of biological processes. The editors of this book hope that the chapters, written by leading scientists in the field, will attract students and scientists from different disciplines, provide them with an authentic insight into this young field of research, allow them to evaluate experimental methods and results, and thereby give them support for their own research. Lausanne Rudolf Rigler September 2007 Horst Vogel v Contents 1 Nanophotonics and Single Molecules. . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 W. E. Moerner, P. James Schuck, David P.
Editors and Affiliations
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Laboratory of Medical Biophysics, MBB, Karolinska Institute, Stockolm, Sweden
R. Rigler
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Laboratory of Physical Chemistry of Polymers and Membranes Institute of Chemical Sciences and Engineering, Swiss Federal Institute of Technology (EPFL), Lausanne, Switzerland
H. Vogel
