Springer Series on Biofilms

Control of Biofilm Infections by Signal Manipulation

Editors: Balaban, Naomi (Ed.)

  • A vital work that provides new approaches to biofilm infections that are largely untreatable by conventional antibiotics
  • Complete with 53 illustrations and online files with updates
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Buy this book

eBook $179.00
price for USA (gross)
  • ISBN 978-3-540-73853-4
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $229.00
price for USA
  • ISBN 978-3-540-73852-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $229.00
price for USA
  • ISBN 978-3-642-09309-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

The medical miracle of antibiotics is being eroded by the emergence and spread of bacterial drug resistance. This is compounded by the fact that bacterial biofilms are believed to be a common cause of persistent infections, when because growing in biofilms, bacteria are protected from the host’s immune response and from antibiotics. In addition, biofilms may spawn systemic infections by sloughing of planktonic bacteria, leading to dissemination, bacteremia, sepsis, and death. The number of patients affected by and dying from what can be considered as a "biofilm disease" is higher than heart disease and cancer combined, making medical biofilms the biggest single disease that the healthcare system is facing today.
This book describes the molecular mechanisms of cell-to-cell communication among bacterial cells in a biofilm, the development of antibiofilm inhibitors, like quorum-sensing inhibitors, and the use of biofilm inhibitors to prevent and treat bacterial infections in humans and other animals.

Table of contents (10 chapters)

  • Introduction

    Balaban, Naomi (et al.)

    Pages 1-11

  • Bacterial Cell-to-cell Communication (Quorum Sensing)

    Givskov, Michael (et al.)

    Pages 13-38

  • Detection In Vitro of Quorum-Sensing Molecules and Their Inhibitors

    McLean, Robert J.C. (et al.)

    Pages 39-50

  • Quorum-Sensing Inhibitory Compounds

    Ren, Dacheng (et al.)

    Pages 51-77

  • Mathematical Modeling of Quorum-Sensing Control in Biofilms

    Ward, John

    Pages 79-108

Buy this book

eBook $179.00
price for USA (gross)
  • ISBN 978-3-540-73853-4
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $229.00
price for USA
  • ISBN 978-3-540-73852-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $229.00
price for USA
  • ISBN 978-3-642-09309-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Control of Biofilm Infections by Signal Manipulation
Editors
  • Naomi Balaban
Series Title
Springer Series on Biofilms
Series Volume
2
Copyright
2008
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-540-73853-4
DOI
10.1007/978-3-540-73853-4
Hardcover ISBN
978-3-540-73852-7
Softcover ISBN
978-3-642-09309-8
Series ISSN
1863-9607
Edition Number
1
Number of Pages
XVI, 175
Number of Illustrations and Tables
43 b/w illustrations, 13 illustrations in colour
Topics