Overview
- Internationally well known experts presented their most recent findings on the fast developing kinase field
- Outstanding interest for basic researchers and pharmaceutical industry
Part of the book series: Ernst Schering Foundation Symposium Proceedings (SCHERING FOUND, volume 2007/3)
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Table of contents (9 papers)
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Front Matter
Keywords
About this book
Protein phosphorylation is an essential post-translational modification that modulates cell–cell communication. Substrate phosphorylation by protein kinases controls intracellular signal transduction pathways that mediate cell proliferation, migration, differentiation, and metabolism. The importance of the protein kinase family is underscored by numerous disease states that arise due to dysregulation of kinase activity. Recent progress in understanding the molecular regulation of kinases has led to the development of new therapeutics based on the inhibition of kinase activity. Inhibitors that target protein kinases have proven efficacious in clinical settings and their continued development is the current focus of many drug discovery groups.
Bibliographic Information
Book Title: Sparking Signals
Book Subtitle: Kinases as Molecular Signaltransducers and Pharmacological Drug Targets in Inflammation
Editors: G. Baier, B. Schraven, U. Zügel, A. von Bonin
Series Title: Ernst Schering Foundation Symposium Proceedings
DOI: https://doi.org/10.1007/978-3-540-73501-4
Publisher: Springer Berlin, Heidelberg
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer-Verlag Berlin Heidelberg 2008
Hardcover ISBN: 978-3-540-73500-7Published: 11 April 2008
Softcover ISBN: 978-3-642-09262-6Published: 25 November 2010
eBook ISBN: 978-3-540-73501-4Published: 19 March 2008
Series ISSN: 0947-6075
Edition Number: 1
Number of Pages: XIV, 187
Topics: Pharmacology/Toxicology, Immunology, Biochemistry, general