Nucleic Acids and Molecular Biology

Protein Engineering

Editors: Koehrer, Caroline, RajBhandary, Uttam L. (Eds.)

  • Describes, for the first time in book form, state-of-the-art concepts and methods (including their applications)
  • Shows the broad range of methodologies developed in the field, from DNA shuffling and domain swapping to protein splicing, protein modification and unnatural amino acid mutagenesis via genetic code expansion
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eBook $259.00
price for USA (gross)
  • ISBN 978-3-540-70941-1
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  • Immediate eBook download after purchase
Hardcover $329.00
price for USA
  • ISBN 978-3-540-70937-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $329.00
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  • ISBN 978-3-642-08992-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Site-specific mutagenesis of DNA, developed some thirty years ago, has proven to be one of the most important advances in biology. By allowing the site-specific replacement of any amino acid in a protein with one of the other nineteen amino acids, it ushered in the new era of "Protein Engineering". The field of protein engineering has, however, evolved rapidly since then and the last fifteen years have witnessed remarkable advances through the use of new chemical, biochemical and molecular biological tools towards the synthesis and manipulation of proteins. The chapters included in this book reflect the rapid evolution of protein engineering and its many applications in basic research, biotechnology, material sciences and therapy. This book will provide the reader with an introduction to state-of the-art concepts and methods and will be of use to anyone interested in the study of proteins, in academia as well as in industry.

Table of contents (12 chapters)

  • Understanding Enzyme Mechanism through Protein Chimeragenesis

    Goodey, N. M. (et al.)

    Pages 1-27

  • Chemical Protein Engineering: Synthetic and Semisynthetic Peptides and Proteins

    Merkel, L. (et al.)

    Pages 29-64

  • Native Chemical Ligation: SemiSynthesis of Post-translationally Modified Proteins and Biological Probes

    Vogel Taylor, E. (et al.)

    Pages 65-96

  • Chemical Methods for Mimicking Post-Translational Modifications

    van Kasteren, S. I. (et al.)

    Pages 97-125

  • Noncanonical Amino Acids in Protein Science and Engineering

    Beatty, K. E. (et al.)

    Pages 127-153

Buy this book

eBook $259.00
price for USA (gross)
  • ISBN 978-3-540-70941-1
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $329.00
price for USA
  • ISBN 978-3-540-70937-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $329.00
price for USA
  • ISBN 978-3-642-08992-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Protein Engineering
Editors
  • Caroline Koehrer
  • Uttam L. RajBhandary
Series Title
Nucleic Acids and Molecular Biology
Series Volume
22
Copyright
2009
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
Distribution Rights
Distribution rights for India: Atlantic Pub. & Distr. (P) Ltd., New Delhi, India
eBook ISBN
978-3-540-70941-1
DOI
10.1007/978-3-540-70941-1
Hardcover ISBN
978-3-540-70937-4
Softcover ISBN
978-3-642-08992-3
Series ISSN
0933-1891
Edition Number
1
Number of Pages
XI, 347
Topics