Current Topics in Microbiology and Immunology

Plant-produced Microbial Vaccines

Editors: Karasev, Alexander V. (Ed.)

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About this book

In recent years, plants have been increasingly explored for production of biomedicines and vaccine components. The two main advantages of plant systems are low cost and a greater potential for scalability as compared to microbial or animal systems. An additional advantage from the public health point of view is high safety compared to animal systems, which is important for vaccine production: there are no known plant pathogens capable of replicating in animals, and in humans in particular. A particular antigen or a protein has to be expressed in a plant using one of many available platforms; this antigen/protein subsequently needs to be purified or processed, and later formulated into a vaccine or a therapeutic; these need to be delivered to a human or animal body via an appropriate route. Naturally, all these vaccines and therapeutics must be subjected to regulatory approvals prior to their use. Thus, the challenge is to adapt plant-based platforms for production of cost-efficient biomedicals that can be approved by FDA for use as vaccine components or therapeutics which will be competitive against existing vaccines and drugs. Production of vaccine components and other biomedicals in plants has a great potential in medicine and veterinary science.

Table of contents (6 chapters)

  • Plant Vaccines: An Immunological Perspective

    Hooper, D. C.

    Pages 1-11

  • Display of Peptides on the Surface of Tobacco Mosaic Virus Particles

    Smith, M. L. (et al.)

    Pages 13-31

  • Chloroplast-Derived Vaccine Antigens and Biopharmaceuticals: Expression, Folding, Assembly and Functionality

    Chebolu, S. (et al.)

    Pages 33-54

  • Production of Antibodies in Plants: Approaches and Perspectives

    Ko, K. (et al.)

    Pages 55-78

  • Plant Production of Veterinary Vaccines and Therapeutics

    Hammond, R. W. (et al.)

    Pages 79-102

Buy this book

eBook $149.00
price for USA (gross)
  • ISBN 978-3-540-70868-1
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $189.00
price for USA
  • ISBN 978-3-540-70857-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $189.00
price for USA
  • ISBN 978-3-642-08983-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Plant-produced Microbial Vaccines
Editors
  • Alexander V. Karasev
Series Title
Current Topics in Microbiology and Immunology
Series Volume
332
Copyright
2009
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-540-70868-1
DOI
10.1007/978-3-540-70868-1
Hardcover ISBN
978-3-540-70857-5
Softcover ISBN
978-3-642-08983-1
Series ISSN
0070-217X
Edition Number
1
Number of Pages
X, 120
Number of Illustrations and Tables
16 b/w illustrations, 10 illustrations in colour
Topics