Pathogenesis and Treatment of Acne and Rosacea

1. Front Matter

   Pages i-xxviii

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2. The Pilosebaceous Unit

   1. Front Matter

      Pages 1-1

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   2. The Sebaceous Gland Through the Centuries: A Difficult Path to Independence

      • Carlo Gelmetti

      Pages 3-8

   3. Embryology of the Pilosebaceous Unit

      • Vladimir A. Botchkarev, Michael Y. Fessing

      Pages 9-17

   4. Molecular Aspects of Sebaceous Differentiation

      • Christos C. Zouboulis, Georgios Nikolakis, Clio Dessinioti

      Pages 19-26

   5. Anatomy of the Sebaceous Gland

      • Fragkiski Tsatsou, Christos C. Zouboulis

      Pages 27-31

   6. Sebum and Sebaceous Lipids

      • Apostolos Pappas

      Pages 33-41

   7. Experimental Models of the Sebaceous Gland

      • Christos C. Zouboulis, Clio Dessinioti

      Pages 43-49

3. Acne Vulgaris: Epidemiology

   1. Front Matter

      Pages 51-51

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   2. Acne Epidemiology and Socioeconomic Aspects

      • Christos C. Zouboulis, Clio Dessinioti, Christina Antoniou

      Pages 53-57

4. Pathogenesis of Acne: Classical Aspects

   1. Front Matter

      Pages 59-59

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   2. Acne Pathogenesis: What We Have Learned Over the Years

      • Clio Dessinioti

      Pages 61-70

   3. The Role of Hyperkeratinization

      • Ichiro Kurokawa

      Pages 71-76

   4. The Role of the Sebaceous Gland

      • Christos C. Zouboulis, Evgenia Makrantonaki

      Pages 77-90

   5. The Role of Bacteria

      • Mark D. Farrar, Richard A. Bojar

      Pages 91-96

   6. Inflammation in Acne

      • Guy F. Webster

      Pages 97-101

5. Pathogenesis of Acne: Modern Aspects

   1. Front Matter

      Pages 103-103

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   2. A New Concept of Acne Pathogenesis

      • Christos C. Zouboulis, Clio Dessinioti

      Pages 105-107

   3. Acne and Genetics

      • Bodo C. Melnik

      Pages 109-130

   4. Acne and Androgens

      • WenChieh Chen, Christos C. Zouboulis

      Pages 131-134

This book, written by experts from across the world, provides comprehensive coverage of acne and rosacea, focusing in particular on pathogenesis and treatment but also considering clinical aspects, prognostic factors, and impacts on quality of life. Both standard knowledge and important, clinically relevant insights that have emerged over the past decade are presented with the goal of assisting the reader in understanding these diseases and improving treatment outcome. It is explained how high-level research has recently given rise to a variety of new concepts in etiology and treatment, and emerging trends are also discussed. The book is in a reader-friendly format that highlights core messages with a very practical and clinical focus. Pathogenesis and Treatment of Acne and Rosacea will be an indispensable reference for all physicians who care for patients with acne or rosacea and for scientists working in the field.

• Laser
• Management of acne
• Phototherapy
• Skin disaese

“This is the most complete reference I have encountered on the pathogenesis and treatment of acne and rosacea. … The audience is dermatologists. … If you are searching for the definitive and comprehensive book on acne, this is the new go-to book.” (Patricia Wong, Doody's Book Reviews, May, 2015)

• Departments of Dermatology, Venereology, Allergology, and Immunology, Dessau Medical Center, Dessau, Germany

  Christos C. Zouboulis

• Department of Dermatology, Andreas Syngros Hospital, University of Athens, Athens, Greece

  Andreas D. Katsambas

• Department of Dermatology, University of Pennsylvania, Philadelphia, USA

  Albert M. Kligman

Policies and ethics