Genome Dynamics and Stability

Recombination and Meiosis

Models, Means, and Evolution

Editors: Egel, Richard, Lankenau, Dirk (Eds.)

  • Together with the preceding volume, covers all major aspects of meiotic research
  • Chapters written by expert researchers who have significantly contributed to progress in their fields
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eBook $289.00
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  • ISBN 978-3-540-68984-3
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Hardcover $369.00
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  • ISBN 978-3-540-68983-6
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Softcover $369.00
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  • ISBN 978-3-642-08850-6
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About this book

Once per life cycle, mitotic nuclear divisions are replaced by meiosis I and II—reducing chromosome number from the diploid level to a haploid genome and recombining chromosome arms by crossing-over. In animals, all this happens during formation of eggs and sperm—in yeasts before spore formation. The mechanisms of reciprocal exchange at crossover/chiasma sites are central to mainstream meiosis. To initiate the meiotic exchange of DNA, surgical cuts are made as a form of calculated damage that subsequently is repaired by homologous recombination. These key events are accompanied by ancillary provisions at the level of chromatin organization, sister chromatid cohesion and differential centromere connectivity. Great progress has been made in recent years in our understanding of these mechanisms. Questions still open primarily concern the placement of and mutual coordination between neighboring crossover events.

Of overlapping significance, this book features two comprehensive treatises of enzymes involved in meiotic recombination, as well as the historical conceptualization of meiotic phenomena from genetical experiments. More specifically, these mechanisms are addressed in yeasts as unicellular model eukaryotes. Furthermore, evolutionary subjects related to meiosis are treated.

Table of contents (9 chapters)

  • Evolution of Models of Homologous Recombination

    Haber, James E.

    Pages 1-64

  • Searching for Homology by Filaments of RecA-Like Proteins

    Prévost, Chantal

    Pages 65-89

  • Biochemistry of Meiotic Recombination: Formation, Processing, and Resolution of Recombination Intermediates

    Ehmsen, Kirk T. (et al.)

    Pages 91-164

  • Meiotic Chromatin: The Substrate for Recombination Initiation

    Lichten, Michael

    Pages 165-193

  • Meiotic Recombination in Schizosaccharomyces pombe: A Paradigm for Genetic and Molecular Analysis

    Cromie, Gareth (et al.)

    Pages 195-230

Buy this book

eBook $289.00
price for USA (gross)
  • ISBN 978-3-540-68984-3
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $369.00
price for USA
  • ISBN 978-3-540-68983-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $369.00
price for USA
  • ISBN 978-3-642-08850-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Recombination and Meiosis
Book Subtitle
Models, Means, and Evolution
Editors
  • Richard Egel
  • Dirk Lankenau
Series Title
Genome Dynamics and Stability
Series Volume
3
Copyright
2008
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-540-68984-3
DOI
10.1007/978-3-540-68984-3
Hardcover ISBN
978-3-540-68983-6
Softcover ISBN
978-3-642-08850-6
Series ISSN
1861-3373
Edition Number
1
Number of Pages
XXI, 390
Topics