Springer Series on Biofilms

The Role of Biofilms in Device-Related Infections

Editors: Shirtliff, Mark E., Leid, Jeff G. (Eds.)

  • Provides the reader with the science and microbiology behind one of the burgeoning increases in infectious disease, indwelling medical device infections

Buy this book

eBook $179.00
price for USA (gross)
  • ISBN 978-3-540-68119-9
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $229.00
price for USA
  • ISBN 978-3-540-68113-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $229.00
price for USA
  • ISBN 978-3-642-08779-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Approximately 60% of all hospital-associated infections, over one million cases per year, are due to biofilms that have formed on indwelling medical devices. Device-related biofilm infections increase hospital stays and add over one billion dollars/year to U.S. hospitalization costs. Since the use and the types of indwelling medical devices commonly used in modern healthcare are continuously expanding, especially with an aging population, the incidence of biofilm infections will also continue to rise. The central problem with microbial biofilm infections of foreign bodies is their propensity to resist clearance by the host immune system and all antimicrobial agents tested to date. In fact, compared to their free floating, planktonic counterparts, microbes within a biofilm are 50 – 500 times more resistant to antimicrobial agents. Therefore, achieving therapeutic and non-lethal dosing regimens within the human host is impossible. The end result is a conversion from an acute infection to one that is persistent, chronic, and recurrent, most often requiring device removal in order to eliminate the infection. This text will describe the major types of device-related infections, and will explain the host, pathogen, and the unique properties of their interactions in order to gain a better understanding of these recalcitrant infections.

Table of contents (10 chapters)

  • Microbial Ecology of Human Skin and Wounds

    James, G. (et al.)

    Pages 1-14

  • Infections of Orthopaedic Implants and Devices

    Brady, Rebecca A. (et al.)

    Pages 15-55

  • Biofilms and Aseptic Loosening

    Smeltzer, Mark S. (et al.)

    Pages 57-74

  • Biofilms and Ventilation

    Thomas, J. G. (et al.)

    Pages 75-107

  • Biofilm Formation on Natural Teeth and Dental Implants: What is the Difference?

    Armellini, Debora (et al.)

    Pages 109-122

Buy this book

eBook $179.00
price for USA (gross)
  • ISBN 978-3-540-68119-9
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $229.00
price for USA
  • ISBN 978-3-540-68113-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $229.00
price for USA
  • ISBN 978-3-642-08779-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Loading...

Recommended for you

Loading...

Bibliographic Information

Bibliographic Information
Book Title
The Role of Biofilms in Device-Related Infections
Editors
  • Mark E. Shirtliff
  • Jeff G. Leid
Series Title
Springer Series on Biofilms
Series Volume
3
Copyright
2009
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-540-68119-9
DOI
10.1007/978-3-540-68119-9
Hardcover ISBN
978-3-540-68113-7
Softcover ISBN
978-3-642-08779-0
Series ISSN
1863-9607
Edition Number
1
Number of Pages
XII, 272
Number of Illustrations and Tables
14 b/w illustrations, 17 illustrations in colour
Topics