Current Topics in Microbiology and Immunology

Signal Transduction and the Coordination of B Lymphocyte Development and Function II

Translation of BCR Signals to Specific Physiologic Outcomes

Editors: Justement, Louis B., Siminovitch, Katherine A. (Eds.)

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About this book

This volume provides a review of current research in the field of B cell development and differentiation with particular emphasis on signal transduction processes. The volume is divided into two parts that focus, respectively, on the basic biochemical pathways which regulate B cell biology and the role of signal transduction processes in regulating various aspects of B cell function, development and differentiation. In this second part the molecular processes involved in translating BCR engagement to specific biological outcomes are reviewed. Topics covered in this part include signal transduction via the pre-B cell antigen receptor complex, the control of immunoglobulin gene recombination and allelic exclusion, and molecular regulation of positive and negative selection. These latter chapters present information regarding processes which are critical for the B cell response to foreign antigen that leads to differentiation into antibody secreting plasma.

Buy this book

Hardcover $259.00
price for USA
  • ISBN 978-3-540-66003-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $259.00
price for USA
  • ISBN 978-3-642-64064-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Signal Transduction and the Coordination of B Lymphocyte Development and Function II
Book Subtitle
Translation of BCR Signals to Specific Physiologic Outcomes
Editors
  • Louis B. Justement
  • Katherine A. Siminovitch
Series Title
Current Topics in Microbiology and Immunology
Series Volume
245/2
Copyright
2000
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
Hardcover ISBN
978-3-540-66003-3
Softcover ISBN
978-3-642-64064-3
Series ISSN
0070-217X
Edition Number
1
Number of Pages
XV, 172
Topics