Advances in Anatomy, Embryology and Cell Biology

The Pineal Organ, Its Hormone Melatonin, and the Photoneuroendocrine System

Authors: Korf, Werner, Schomerus, Christof, Stehle, Jörg H.

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  • ISBN 978-3-642-58932-4
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About this book

This book offers a synoptic view of comparative anatomical, ultrastructural, cell and molecular biological investigations of the pineal organ. It considers morphological, immunocytochemical and functional features of pineal photoreceptors and neuroendocrine pinealocytes as well as the afferent and efferent innervation of the pineal organ. Special emphasis is placed on receptor mechanisms, second messenger systems (Ca2+ and cyclic AMP), transcription factors (e.g. cyclic AMP response element binding protein, CREB, and inducible cyclic AMP early repressor, ICER) and their roles for regulation of melatonin biosynthesis. Finally, the action, targets and receptors of melatonin are dealt with. The data presented stress the functional significance of the pineal organ and its hormoe melatonin as important components of the photoneuroendocrine system which allows man and animals to measure and keep the time. They also prove the pineal organ as a very suitable model to study signal transduction mechanisms in both photoreceptors and neuroendocrine cells by means of a variety of modern techniques.

Table of contents (7 chapters)

  • Introduction

    Korf, H.-W. (et al.)

    Pages 1-8

  • Phylogenetic Development and Gross Anatomy of the Pineal Complex

    Korf, H.-W. (et al.)

    Pages 9-11

  • Pineal Cell Biology and Innervation

    Korf, H.-W. (et al.)

    Pages 13-44

  • Receptor Mechanisms and Second Messenger Systems Involved in the Regulation of the Melatonin Biosynthesis

    Korf, H.-W. (et al.)

    Pages 45-58

  • Pineal Transcription Factors and Their Possible Roles for the Regulation of the Melatonin Biosynthesis

    Korf, H.-W. (et al.)

    Pages 59-71

Buy this book

eBook $149.00
price for USA (gross)
  • ISBN 978-3-642-58932-4
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $189.00
price for USA
  • ISBN 978-3-540-64135-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
The Pineal Organ, Its Hormone Melatonin, and the Photoneuroendocrine System
Authors
Series Title
Advances in Anatomy, Embryology and Cell Biology
Series Volume
146
Copyright
1998
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-642-58932-4
DOI
10.1007/978-3-642-58932-4
Softcover ISBN
978-3-540-64135-3
Series ISSN
0301-5556
Edition Number
1
Number of Pages
X, 102
Number of Illustrations and Tables
27 b/w illustrations
Topics