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Reviews of Physiology, Biochemistry and Pharmacology

  • Book
  • © 2002

Overview

Part of the book series: Reviews of Physiology, Biochemistry and Pharmacology (REVIEWS, volume 144)

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Table of contents (3 chapters)

  1. Front Matter

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  2. Phospholipase D—Structure, regulation and function

    • J. H. Exton
    Pages 1-94

  3. Endotoxin tolerance — Mechanisms and beneficial effects in bacterial infection

    • M. D. Lehner, T. Hartung
    Pages 95-141

  4. The structural basis of g-protein-coupled receptor function and dysfunction in human diseases

    • T. Schöneberg, A. Schulz, T. Gudermann
    Pages 144-227
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Keywords

About this book

In this volume of Reviews there are three outstanding articles, one on phspholipase D, an enzyme that is widely distributed in bacteria, protozoa, fungi, plants and animals. Phospholipase D carries out a transphosphatidylation reaction, which is unique to this enzyme. This review is focussed on mammalian PLDs. The second review deals with endotoxin tolerance, the term which describes the phenomenon that immune responses and metabolic changes are mitigated after repeated LPS administration. The third article summarizes the current knowledge relevant to understanding the molecular basis of GPCR function and focusses on the underlying mechanisms of GPCR malfunctions responsible for diferent human diseases.

Bibliographic Information

  • Book Title: Reviews of Physiology, Biochemistry and Pharmacology

  • Series Title: Reviews of Physiology, Biochemistry and Pharmacology

  • DOI: https://doi.org/10.1007/BFb0116584

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE, part of Springer Nature 2002

  • Softcover ISBN: 978-3-662-31007-6Published: 18 April 2014

  • eBook ISBN: 978-3-540-45534-9Published: 11 December 2007

  • Series ISSN: 0303-4240

  • Series E-ISSN: 1617-5786

  • Edition Number: 1

  • Number of Pages: V, 227

  • Number of Illustrations: 29 b/w illustrations, 12 illustrations in colour

  • Topics: Human Physiology, Biochemistry, general, Pharmacology/Toxicology

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