Progress in Molecular and Subcellular Biology

Regulation of Alternative Splicing

Editors: Jeanteur, Philippe (Ed.)

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About this book

The generality and quantitative extent of alternative splicing have only now begun to be fully appreciated. The first draft of the complete human genome led to the surprisingly low figure of about 32,000 genes. The extensive use of alternative splicing and its consequences in terms of coding capacity could account for this discrepancy and help fill the complexity gap between the genome and the proteome. After a computer-based assessment of the frequency of alternative splicing, this book addresses mechanistic aspects followed by examples of its involvement in important cellular processes. Finally, it raises the possibility of artificial modulation of alternative splicing by antisense nucleotides.

Table of contents (8 chapters)

  • Prediction and Statistical Analysis of Alternatively Spliced Exons

    Thanaraj, T. A. (et al.)

    Pages 1-31

  • Multiple Roles of the SR Protein Family in Splicing Regulation

    Sanford, J. R. (et al.)

    Pages 33-58

  • Heterogeneous Nuclear Ribonucleoprotein Particle A/B Proteins and the Control of Alternative Splicing of the Mammalian Heterogeneous Nuclear Ribonucleoprotein Particle A1 Pre-mRNA

    Chabot, B. (et al.)

    Pages 59-88

  • Phosphorylation-Dependent Control of the Pre-mRNA Splicing Machinery

    Soret, J. (et al.)

    Pages 89-126

  • Splicing Regulation in Drosophila Sex Determination

    Förch, P. (et al.)

    Pages 127-151

Buy this book

eBook $229.00
price for USA (gross)
  • ISBN 978-3-662-09728-1
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $299.00
price for USA
  • ISBN 978-3-540-43833-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $299.00
price for USA
  • ISBN 978-3-642-07858-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Regulation of Alternative Splicing
Editors
  • Philippe Jeanteur
Series Title
Progress in Molecular and Subcellular Biology
Series Volume
31
Copyright
2003
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-662-09728-1
DOI
10.1007/978-3-662-09728-1
Hardcover ISBN
978-3-540-43833-5
Softcover ISBN
978-3-642-07858-3
Series ISSN
0079-6484
Edition Number
1
Number of Pages
XIII, 245
Number of Illustrations and Tables
77 b/w illustrations, 1 illustrations in colour
Topics