Research and Perspectives in Neurosciences

Neuronal Death by Accident or by Design

Editors: Henderson, C.E., Green, D., Mariani, J., Christen, Y. (Eds.)

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About this book

Four chapters represent the intense current effort to understand the way in which the mitochondrion controls the activation of the final stages of cell death. Another four articles attack the problem from the other side. How do specific insults in particular human or mouse neuro-degenerative diseases translate into mechanisms that will not only allow us to better understand what is happening in these patients but also, with luck, allow for development of more efficient and specific drugs in the future? Firstly, the concept of a central common cell death pathway, originally derived from studies on the nematode, has been an outstanding productive paradigm in bringing together different strands of research. Secondly, truly striking links have been made between results obtained in the culture dish (or even cell-free systems) and the diseased human brain.

Table of contents (11 chapters)

  • Mitochondria and Apoptosis, the Stepping Stones on the Path to Death

    Ethell, D. W. (et al.)

    Pages 1-13

  • Mitochondrial Membrane Permeabilization in Physiological and Pathological Cell Death

    Ravagnan, L. (et al.)

    Pages 15-26

  • Bcl-2 Family Members and Permeabilization of the Outer Mitochondrial Membrane

    Terradillos, O. (et al.)

    Pages 27-32

  • Roles for Fas in Programmed Cell Death of Motoneurons

    Raoul, C. (et al.)

    Pages 33-45

  • Events that Commit Neurons to Die After Trophic Factor Deprivation

    Putcha, G. V. (et al.)

    Pages 47-60

Buy this book

eBook $159.00
price for USA (gross)
  • ISBN 978-3-662-04333-2
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $209.00
price for USA
  • ISBN 978-3-540-41777-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $209.00
price for USA
  • ISBN 978-3-642-07517-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Neuronal Death by Accident or by Design
Editors
  • C.E. Henderson
  • D. Green
  • J. Mariani
  • Y. Christen
Series Title
Research and Perspectives in Neurosciences
Copyright
2001
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-662-04333-2
DOI
10.1007/978-3-662-04333-2
Hardcover ISBN
978-3-540-41777-4
Softcover ISBN
978-3-642-07517-9
Series ISSN
0945-6082
Edition Number
1
Number of Pages
XI, 154
Number of Illustrations and Tables
40 b/w illustrations, 18 illustrations in colour
Topics