Ernst Schering Foundation Symposium Proceedings

PET Chemistry

The Driving Force in Molecular Imaging

Editors: Schubiger, P.A., Lehmann, L., Friebe, M. (Eds.)

Buy this book

eBook $219.00
price for USA (gross)
  • ISBN 978-3-540-49527-7
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $279.00
price for USA
  • ISBN 978-3-540-32623-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $279.00
price for USA
  • ISBN 978-3-642-42164-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Personalized medicine employing patient-based tailor-made therapeutic drugs is taking over treatment paradigms in a variety of ?elds in oncology and the central nervous system. The success of such therapies is mainly dependent on ef?cacious therapeutic drugs and a selective imaging probe for identi?cation of potential responders as well as therapy monitoring for an early bene?t assessment. Molecular imaging (MI) is based on the selective and speci?c interaction of a molecular probe with a biological target which is visualized through nuclear, magnetic resonance, near infrared or other methods. Therefore it is the method of choice for patient selection and therapy monitoring as well as for speci?c e- point monitoring in modern drug development. PET (positron emitting tomography), a nuclear medical imaging modality, is ideally suited to produce three-dimensional images of various targets or processes. The rapidly increasing demand for highly selective probes for MI strongly pushes the development of new PET tracers and PET chemistry. ‘PET chemistry’ can be de?ned as the study of positron-emitting compounds regarding their synthesis, structure, composition, reactivity, nuclear properties and processes and their properties in natural and - natural environments. In practice PET chemistry is strongly in?uenced by the unique properties of the radioisotopes used (e. g. , half-life, che- cal reactivity, etc. ) and integrates scienti?c aspects of nuclear-, organic-, inorganic- and biochemistry.

Table of contents (8 chapters)

  • Fluorine-18 Labeling of Small Molecules: The Use of 18F-Labeled Aryl Fluorides Derived from No-Carrier-Added [18F]Fluoride as Labeling Precursors

    F. Wuest

    Pages 51-78

  • Fluorine-18 Labeling of Peptides and Proteins

    H. J. Wester, M. Schottelius

    Pages 79-111

  • Production of Non-standard PET Radionuclides and the Application of Radiopharmaceuticals Labeled with these Nuclides

    M. J. Welch, R. Laforest, J. S. Lewis

    Pages 159-181

  • Carbon-11 Labeling Chemistry Based upon [11C]Methyl Iodide

    F. Wuest, M. Berndt, T. Kniess

    Pages 183-213

  • 68Ga-PET Radiopharmacy: A Generator-Based Alternative to 18F-Radiopharmacy

    H. R. Maecke, J. P. André

    Pages 215-242

Buy this book

eBook $219.00
price for USA (gross)
  • ISBN 978-3-540-49527-7
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $279.00
price for USA
  • ISBN 978-3-540-32623-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $279.00
price for USA
  • ISBN 978-3-642-42164-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Loading...

Recommended for you

Loading...

Bibliographic Information

Bibliographic Information
Book Title
PET Chemistry
Book Subtitle
The Driving Force in Molecular Imaging
Editors
  • P.A. Schubiger
  • L. Lehmann
  • M. Friebe
Series Title
Ernst Schering Foundation Symposium Proceedings
Series Volume
62
Copyright
2007
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-540-49527-7
DOI
10.1007/978-3-540-49527-7
Hardcover ISBN
978-3-540-32623-6
Softcover ISBN
978-3-642-42164-8
Series ISSN
0947-6075
Edition Number
1
Number of Pages
XII, 345
Topics