Pediatric Oncology

Neuroblastoma

Editors: Cheung, Nai-Kong V., Cohn, Susan L. (Eds.)

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  • ISBN 978-3-540-26616-7
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About this book

Neuroblastoma is a medical enigma. As a childhood neoplasm arising from neural crest cells, it is characterized by diverse clinical behaviors ranging from spontaneous remission to rapid tumor progression and death. Although clinical outcome can be predicted to a large extent by the stage of disease and the age at diagnosis, an in-depth understanding of its clinico-pathological behavior, now greatly aided by sophisticated molecular genetic profiling, will improve diagnostic precision and refine risk-based therapies. Comprehensive international efforts have advanced our understanding of tumor biology and improved the clinical management of children with neuroblastoma. This book reviews our current understanding of the genes and biological pathways that contribute to neuroblastoma pathogenesis, modern risk-based treatment approaches for these patients, and recent advances in biologically based therapy. It provides a concise up-to-date reference for practitioners, students, and researchers.

Reviews

From the reviews:

"This comprehensive, multiauthored book describes the epidemiologic, genetic, biologic, pathologic, diagnostic and therapeutic aspects of neuroblastoma in 19 concise, informative chapters. … Production is excellent with clear illustrations and helpful tables. … those with an interest in cancer investigation and whose consultations include a number of pediatric cancer patients, this excellent book illuminates scientific, diagnostic, and treatment issues that will increase their understanding of neuroblastoma and of the difficulties encountered in combating this and other childhood neoplasms. Overall grade: Outstanding." (B. D. Fletcher, Pediatric Radiology, Vol. 36, 2006)


Table of contents (7 chapters)

  • Epidemiology

    Andrew F. Olshan

    Pages 1-5

  • Genetics

    John M. Maris, Garrett M. Brodeur

    Pages 21-26

  • Clinical Presentation

    Frank Berthold, Thorsten Simon

    Pages 63-85

  • Anatomic and Functional Imaging

    Sara J. Abramson, Barry L. Shulkin

    Pages 109-122

  • Treatment of Neuroblastoma

    Brian H. Kushner, Susan L. Cohn, Katherine K. Matthay, Nai-Kong V. Cheung, Michael P. La Quaglia, Daphne A. Haas-Kogan, Suzanne L. Wolden, Stephan A. Grupp, Irene Y. Cheung, Peter F. Ambros

    Pages 123-192

Buy this book

eBook $159.00
price for USA (gross)
  • ISBN 978-3-540-26616-7
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
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Bibliographic Information

Bibliographic Information
Book Title
Neuroblastoma
Editors
  • Nai-Kong V. Cheung
  • Susan L. Cohn
Series Title
Pediatric Oncology
Copyright
2005
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-540-26616-7
DOI
10.1007/b137762
Series ISSN
1613-5318
Edition Number
1
Number of Pages
XV, 300
Number of Illustrations and Tables
30 b/w illustrations, 21 illustrations in colour
Topics