Research and Perspectives in Endocrine Interactions

Deciphering Growth

Editors: Carel, J.-C., Kelly, Paul A. (Eds.)

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About this book

Growth is a complex process that is essential to life. Not only does size play an important role in the process of cellular proliferation, but body size is also a critical factor in determining which organisms live longer. In mammals, the major factors involved in the regulation of body growth are known: insulin-like growth factors (IGF) are key regulators of somatic growth. Growth hormone (GH), secreted by the pituitary gland, directly regulates circulating levels of IGF-I, which is the major coordinator of spatio-temporal growth of the organism. In humans, growth involves a number of specific characteristics not found in other species. These include rapid intrauterine growth, deceleration just after birth, a mid-childhood growth spurt, a second deceleration before puberty, an adolescent growth spurt, and finally full statural growth, which is seen somewhat later. The combined knowledge concerning the endocrine and paracrine aspects of growth have led to the introduction of treatment regimens, most effective in GH-deficient children.

Table of contents (1 chapters)

  • The GH/IGF-1 Axis: Insights from Animal Models

    Martin Holzenberger, et al.

    Pages

Buy this book

eBook $189.00
price for USA (gross)
  • ISBN 978-3-540-28902-9
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $239.00
price for USA
  • ISBN 978-3-540-26192-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $239.00
price for USA
  • ISBN 978-3-642-42129-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Deciphering Growth
Editors
  • J.-C. Carel
  • Paul A. Kelly
Series Title
Research and Perspectives in Endocrine Interactions
Copyright
2005
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-540-28902-9
DOI
10.1007/3-540-28902-X
Hardcover ISBN
978-3-540-26192-6
Softcover ISBN
978-3-642-42129-7
Series ISSN
1861-2253
Edition Number
1
Number of Pages
XIII, 155
Topics