Radiation Oncology

Multimodal Concepts for Integration of Cytotoxic Drugs

Editors: Brown, Martin J., Mehta, M.P., Nieder, Carsten (Eds.)

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About this book

Over recent decades, combined modality treatment has drastically improved the cure rates for various malignant tumors. Further progress is expected through the design of sound combinations involving recently developed drugs. The first part of this book summarizes the rationale and the preclinical data for combined treatment with ionizing radiation and pharmaceutical agents. Individual chapters focus on different forms of combined treatment, with due consideration being given to a range of drugs and to emerging combinations with small molecules and antibodies, derived from recent advances in molecular oncology. The second part of the book comprises a series of disease-specific chapters in which the clinical results of combined modality treatment are presented. In addition, the topics of acute and late toxicity, supportive treatment and tolerance in elderly patients are reviewed. All of the chapters have been written by basic scientists and clinicians who are acknowledged experts in the field. The text is specifically designed to be accessible to professionals from the various disciplines involved in multidisciplinary cancer care and to residents in radiation oncology training programs.

About the authors

J. Martin Brown, PhD, is a Professor of Radiation Oncology at Stanford University. He was president of the Radiation Research Society and member of several program and award committees of the American Association for Cancer Research. Dr. Brown is currently the senior editor for biology for the International Journal of Radiation Oncology Biology Physics. He has received a number of awards, including an NIH M.E.R.I.T. Award, the Research Award from the Radiation Research Society, the 1999 Cain Memorial Award from the American Association for Cancer Research, the 1999 ASTRO Gold Medal, and the Weiss Medal from the Association for Radiation Research.

Minesh P. Mehta, MD, is Professor and Chairman of the Department of Human Oncology, University of Wisconsin Medical School, Madison. He is the Chairman of the Radiation Therapy Oncology Group Brain Tumor Committee and is on the editorial board of the Journal of Neuro-Oncology and the International Journal of Cancer Research.

Carsten Nieder, MD, is head of the Radiation Oncology Section of the Multidisciplinary Cancer Center and deputy head of the Stereotactic Central Nervous System Radiotherapy program, Klinikum rechts der Isar, Munich. He has received a 2-year research scholarship from the Mildred Scheel Foundation and the Hanns Langendorff Award 2003. Dr. Nieder is on the editorial board of Reviews of Recent Randomized Trials.

Table of contents (22 chapters)

  • Biological Basis of Combined Radio- and Chemotherapy

    Belka, Claus (et al.)

    Pages 3-17

  • Combinations of Antimetabolites and Ionizing Radiation

    Harada, Hiroshi (et al.)

    Pages 19-34

  • Combinations of Taxanes and Ionizing Radiation

    Milas, Luka (et al.)

    Pages 35-51

  • Combinations of Topoisomerase Inhibitors and Ionizing Radiation

    Bastasch, Michael (et al.)

    Pages 53-66

  • Combinations of Hypoxia-Targeting Compounds and Radiation-Activated Prodrugs with Ionizing Radiation

    Ahn, G-One (et al.)

    Pages 67-91

Buy this book

eBook $269.00
price for USA (gross)
  • ISBN 978-3-540-35662-2
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $339.00
price for USA
  • ISBN 978-3-540-25655-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $339.00
price for USA
  • ISBN 978-3-642-06505-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Multimodal Concepts for Integration of Cytotoxic Drugs
Editors
  • Martin J. Brown
  • M.P. Mehta
  • Carsten Nieder
Series Title
Radiation Oncology
Copyright
2006
Publisher
Springer-Verlag Berlin Heidelberg
Copyright Holder
Springer-Verlag Berlin Heidelberg
eBook ISBN
978-3-540-35662-2
DOI
10.1007/3-540-35662-2
Hardcover ISBN
978-3-540-25655-7
Softcover ISBN
978-3-642-06505-7
Edition Number
1
Number of Pages
X, 352
Number of Illustrations and Tables
2 b/w illustrations, 12 illustrations in colour
Topics