Klinefelter’s Syndrome

1. Front Matter

   Pages I-XIV

   PDF

2. Background, Recognition and Description of the Syndrome

   • H. F. Klinefelter

   Pages 1-7

3. Incidence of Klinefelter’s Syndrome

   • E. Perwein

   Pages 8-11

4. Genetics and Cytogenetics of Klinefelter’s Syndrome

   • K. D. Zang

   Pages 12-23

5. Klinefelter’s Syndrome in Prenatal Diagnosis: Incidence and Consequences for Genetic Counselling

   • J. Murken, S. Stengel-Rutkowski

   Pages 24-28

6. Klinefelter’s Syndrome: Diagnostic Criteria in Childhood

   • D. Knorr, J. Weil

   Pages 29-37

7. Klinefelter’s Syndrome in Children: A Longitudinal Study of 47, XXY Boys Identified by Population Screening

   • S. G. Ratcliffe

   Pages 38-47

8. The Clinical Appearance of Klinefelter’s Syndrome

   • E. W. Jecht, K.-H. Conrad, O. P. Hornstein

   Pages 48-50

9. Osteoporosis and Klinefelter’s Syndrome

   • M. Horowitz, B. E. C. Nordin, J. Aaron, T. Steurer, R. M. Francis, J. C. Philcox et al.

   Pages 51-61

10. Functional Characteristics of the Hypothalamic-Pituitary Unit in Klinefelter’s Syndrome (Pituitary Hormone Release in Response to Exogenous Estradiol)

    • A. Barbarino, L. De Marinis, A. Mancini

    Pages 62-70

11. Lower Leg Ulcers in Klinefelter’s Syndrome

    • R. Breit

    Pages 71-79

12. Taurodontism in Klinefelter’s Syndrome

    • B. Rossiwall

    Pages 80-84

13. Dermatoglyphics of Klinefelter’s Syndrome

    • P. Saldaña-Garcia

    Pages 85-100

14. Immune Competence in Patients with Klinefelter’s Syndrome

    • J. S. H. Tsung

    Pages 101-108

15. Systemic Lupus Erythematosus and Klinefelter’s Syndrome

    • D. Alarcón-Segovia, J. Sauza

    Pages 109-114

16. Klinefelter’s Syndrome and Testicular Tumors

    • P. Meister

    Pages 115-117

17. Breast Carcinoma in Association with the Klinefelter’s Syndrome

    • O. Scheike, J. Visfeldt, B. Petersen

    Pages 118-126

18. Klinefelter’s Syndrome and Leukemia: Coincidence or Association?

    • S. J. M. Muts-Homsma, J. P. M. Geraedts

    Pages 127-130

19. Histology of Testes in Klinefelter’s Syndrome

    • H.-J. Bandmann, E. Perwein

    Pages 131-136

20. Ultrastructure of the Testis in Klinefelter’s Syndrome

    • Chr. Sigg, Chr. Hedinger

    Pages 137-146

Klinefelter's syndrome occurs relatively frequently, being diagnosed for one in 600 male infants, yet it is probably very rare that it is recognized early enough to make effective treatment possible. Often the person afflicted does not go to a doctor until physical and emotional disturbances have developed on the ba­ sis of the syndrome. The appropriate therapy at the correct time can prevent many of these disturbances. In our andrology outpatient clinic we encountered Klinefelter's syndrome almost three decades ago in patients suffering from impotentia generandi. It was not until later that we dealt with it in our capacities as dematologists. It was observed at a rate too high to be coincidental among younger men suffer­ ing from ulcera crurum. On the other hand, we failed to see the condition during our work as con­ sultants in other specialities, especially internal medicine, although we re­ peatedly attempted to identify it. We should have encountered it at least occa­ sionally in our 10 years working in the Munich hospitals with their more than 4000 beds. It was this imbalance between the allegedly relative frequency of this condition and its rare detection which led us to plan a Klinefelter sympo­ sium. We soon determined, during a first search of the literature, that there was information in many more subject areas that we had expected or even guessed.

• Syndrome
• child
• childhood
• histology
• hormone
• hormones
• testis

• Dermatologische und Allergologische Abteilung, Städtisches Krankenhaus München-Schwabing, München 40, Germany

  Hans-Jürgen Bandmann, Reinhardt Breit, Elmar Perwein

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