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Kinetic Logic: A Boolean Approach to the Analysis of Complex Regulatory Systems

Proceedings of the EMBO Course “Formal Analysis of Genetic Regulation”, Held in Brussels, September 6–16, 1977

  • Conference proceedings
  • © 1979

Overview

Editors:
  1. René Thomas

    1. Department of Molecular Biology, Faculty of Sciences, University of Brussels, Rhode Saint Genèse, Belgium

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Part of the book series: Lecture Notes in Biomathematics (LNBM, volume 29)

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Table of contents (23 papers)

  1. Front Matter

    Pages I-XIII
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  3. Naive boolean analysis

    1. Front Matter

      Pages 61-61
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    2. Combinational systems

      • A. Leussler, P. Van Ham
      Pages 62-85

    3. Sequential Systems

      • A. Leussler, P. Van Ham
      Pages 86-106

    4. Kinetic logic : a boolean analysis of the dynamic behaviour of control circuits

      • R. Thomas
      Pages 107-126

    5. The dynamic behaviour of boolean systems comprising feedback loops

      • R. Thomas
      Pages 127-142

    6. Delphin : a logical machine with incrementable phase delays

      • Philippe Van Ham
      Pages 143-148

    7. Computer Programs for simulation of logical models

      • P. Van Vam, J. L. Dehouck
      Pages 149-163

    8. Net structures for sequential logic

      • J. Florine
      Pages 164-176
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Keywords

About this book

The E M B 0 course on "Formal Analysis of Genetic Regulation" A course entitled "Formal analysis of Genetic Regulation" was held at the University of Brussels from 6 to 16 September 1977 under the auspices of EMBO (European Molecular Biology Organization). As indicated by the title of the book (but not explicitly enough by the title of the course), the main emphasis was put on a dynamic analysis of systems using logical methods, that is, methods in which functions and variables take only a limited number of values - typically two. In this respect, this course was complementary to an EMBO course using continuous methods which was held some months later in Israel by Prof. Segel. People from four very different laboratories took an active part in teaching our course in Brussels : Drs Anne LEUSSLER and Philippe VAN HAM, from the Laboratory of Prof. Jean FLORINE (Laboratoire des Systemes logiques et numeriques, Faculte des Sciences appliquees, Universite Libre de Bruxelles). Dr Stuart KAUFFMAN (Dept. of Biochemistry and Biophysics, School of Medicine, Philadelphia). Prof. Gregoire NICOLlS (Service de Biophysique Theorique, Faculte des Sciences, Universite Libre de Bruxelles) and his temporary coworker Dr David RIGNEY (presently at the Center for Statistical Mechanics and Thermodynamics of the University of Texas at Austin, Texas).

Editors and Affiliations

  • Department of Molecular Biology, Faculty of Sciences, University of Brussels, Rhode Saint Genèse, Belgium

    René Thomas

Bibliographic Information

  • Book Title: Kinetic Logic: A Boolean Approach to the Analysis of Complex Regulatory Systems

  • Book Subtitle: Proceedings of the EMBO Course “Formal Analysis of Genetic Regulation”, Held in Brussels, September 6–16, 1977

  • Editors: René Thomas

  • Series Title: Lecture Notes in Biomathematics

  • DOI: https://doi.org/10.1007/978-3-642-49321-8

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1979

  • Softcover ISBN: 978-3-540-09556-9Published: 01 November 1979

  • eBook ISBN: 978-3-642-49321-8Published: 29 June 2013

  • Series ISSN: 0341-633X

  • Series E-ISSN: 2196-9981

  • Edition Number: 1

  • Number of Pages: XIII, 510

  • Topics: Mathematics, general

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