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Congenital Bleeding Disorders

Diagnosis and Management

  • Book
  • © 2018

Overview

Editors:
  1. Akbar Dorgalaleh

    1. Iran University of Medical Sciences, Departement of Hematology and Blood TransfusionSchool of Allied Medicine, Iran University of Medical Sciences, Tehran, Iran

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  • Offers detailed assistance in the diagnosis and management of bleeding disorders
  • Includes extensive coverage of rare disorders and the challenges that they pose
  • Provides up-to-date guidance on use of the latest treatment options and new products

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Table of contents (16 chapters)

  1. Front Matter

    Pages i-xiv
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  2. An Overview of Hemostasis and Congenital Bleeding Disorders

    1. Front Matter

      Pages 1-1
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    2. An Overview of Hemostasis

      • Akbar Dorgalaleh, Maryam Daneshi, Jamal Rashidpanah, Elaheh Roshani Yasaghi
      Pages 3-26

    3. Congenital Bleeding Disorders

      • Akbar Dorgalaleh, Fariba Rad
      Pages 27-53

  3. Common Bleeding Disorders

    1. Front Matter

      Pages 55-55
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    2. von Willebrand Disease

      • Akbar Dorgalaleh, Shadi Tabibian, Yavar Shiravand, Emmanuel J. Favaloro
      Pages 57-102

    3. Hemophilia A

      • Mohammad Saeed Gholami, Mohsen Valikhani, Akbar Dorgalaleh, Sayed Hamid Mousavi, Behnaz Pezeshkpoor
      Pages 103-137

    4. Hemophilia B

      • Hoda Motlagh, Behnaz Pezeshkpoor, Akbar Dorgalaleh
      Pages 139-160

  4. Rare Bleeding Disorders

    1. Front Matter

      Pages 161-161
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    2. Congenital Fibrinogen Disorders

      • Akbar Dorgalaleh, Alessandro Casini, Parvin Rahmani
      Pages 163-181

    3. Congenital Factor II Deficiency

      • Yadollah Farshi, Akbar Dorgalaleh, Shadi Tabibian
      Pages 183-199

    4. Congenital Factor V Deficiency

      • Shadi Tabibian, Akbar Dorgalaleh, Rodney M. Camire
      Pages 201-218

    5. Multiple Coagulation Factor Deficiency

      • Maryam Sadat Hosseini, Mahmood Shams, Akbar Dorgalaleh, Hassan Mansouritorghabeh
      Pages 219-238

    6. Congenital Factor VII Deficiency

      • Mahmood Shams, Akbar Dorgalaleh
      Pages 239-259

    7. Congenital Factor X Deficiency

      • Fateme Roshanzamir, Akbar Dorgalaleh
      Pages 261-289

    8. Congenital Factor XI Deficiency

      • Tahere Tabatabaei, Akbar Dorgalaleh
      Pages 291-306

    9. Congenital Factor XIII Deficiency

      • Akbar Dorgalaleh, Majid Naderi, Majid Safa
      Pages 307-324

  5. Inherited Platelet Function Disorders

    1. Front Matter

      Pages 325-325
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    2. Glanzmann Thrombasthenia

      • Akbar Dorgalaleh, Man-Chiu Poon, Yavar Shiravand
      Pages 327-355

    3. Bernard-Soulier Syndrome

      • Bahare Ghasemi, Akbar Dorgalaleh
      Pages 357-377
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Keywords

About this book

This book describes in detail the clinical presentation, diagnosis, and management of a wide range of congenital bleeding disorders. It will assist readers in overcoming the significant challenges involved in clinical and laboratory diagnosis and in providing effective clinical care that makes optimal use of new products, including recombinant factor concentrate. The coverage ranges from hemophilia A and B and von Willebrand disease to rare bleeding disorders such as congenital factor V, factor X, factor XI, and factor XIII deficiency and inherited platelet function disorders. The exceptional attention to rarer conditions is of particular importance given the considerable risk of overlooking them during diagnosis, with potential consequences for disease-related morbidity and mortality. The authors are acknowledged specialists in the field from across the world who have particular expertise in the disorder that they discuss. The book will be of value to hematologists, oncologists, pediatricians, laboratory specialists and technicians, general physicians, and trainees. 

Editors and Affiliations

  • Iran University of Medical Sciences, Departement of Hematology and Blood TransfusionSchool of Allied Medicine, Iran University of Medical Sciences, Tehran, Iran

    Akbar Dorgalaleh

About the editor

Akbar Dorgalaleh, hematologist and scientific researcher in the field of congenital bleeding disorders in the Department of Hematology and Blood Transfusion, Iran University of Medical Sciences (IUMS). Dr. Dorgalaleh’s primary interest is the diagnosis and management of congenital bleeding disorders, and he has a special interest in congenital factor XIII deficiency. He acts as a reviewer for several international journals in the field of Hematology and to date has authored about 100 papers that cover all the congenital bleeding disorders, including hemophilia, rare bleeding disorders, and inherited platelet function disorders. He has reported the clinical, laboratory, and molecular characteristics of a very large number of patients with congenital bleeding disorders.  

Bibliographic Information

  • Book Title: Congenital Bleeding Disorders

  • Book Subtitle: Diagnosis and Management

  • Editors: Akbar Dorgalaleh

  • DOI: https://doi.org/10.1007/978-3-319-76723-9

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer International Publishing AG, part of Springer Nature 2018

  • Softcover ISBN: 978-3-030-09565-9Published: 25 December 2018

  • eBook ISBN: 978-3-319-76723-9Published: 25 July 2018

  • Edition Number: 1

  • Number of Pages: XIV, 396

  • Number of Illustrations: 8 b/w illustrations, 85 illustrations in colour

  • Topics: Hematology, Pediatrics

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