Overview
- Nominated as an outstanding Ph.D. thesis by the University of Bologna, Italy
- Offers a comprehensive introduction on the general aspects of chirality and organocatalysis
- Explores both vinylogy and atropisomerism
Part of the book series: Springer Theses (Springer Theses)
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Table of contents (5 chapters)
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Front Matter
Keywords
About this book
This thesis discusses the use of asymmetric organic catalysis for the direct enantioselective synthesis of complex chiral molecules, and by addressing the many aspects of both vinylogy and atropisomerism, it appeals to researchers and scholars interested in both areas.
Organocatalysis is a relatively modern and “hot” topic in the chemical community; it is constantly expanding and its use has been extended to interesting areas like vinylogous reactivity and atropisomerism. Vinylogous systems are very important for their synthetic applications but also pose a number of challenges, the most notable of which are their reduced reactivity and the reduced stereocontrol at these positions. On the other hand, atropisomeric systems are even more important because of the huge potential they have as drugs, ligands and catalysts. Chemists have only recently “recognized” the importance of these two areas and are focusing their efforts on studying them and the challenges they pose.This thesis offers an extensive introduction on the general aspects of chirality and organocatalysis and an equally extensive experimental section that allow nonexperts to understand the discussion section and reproduce the experiments.
Authors and Affiliations
About the author
Nicola Di Iorio was born in 1989. During his studies at the University of Bologna, Italy he spent a year abroad at UCLA (University of California, Los Angeles, USA) before graduating (cum laude) in Industrial Chemistry in October 2013. Immediately afterwards, he started his doctoral studies on asymmetric organocatalysis, focusing particularly on unconventional axial chirality. In February 2017 he received the “Spada Award” for Ph.D. students who have distinguished themselves in productivity, innovation and scientific independence. Two months later, he completed his Ph.D. and is currently working as a postdoc at the Department of Industrial Chemistry at the University of Bologna.
Bibliographic Information
Book Title: New Organocatalytic Strategies for the Selective Synthesis of Centrally and Axially Chiral Molecules
Authors: Nicola Di Iorio
Series Title: Springer Theses
DOI: https://doi.org/10.1007/978-3-319-74914-3
Publisher: Springer Cham
eBook Packages: Chemistry and Materials Science, Chemistry and Material Science (R0)
Copyright Information: Springer International Publishing AG, part of Springer Nature 2018
Hardcover ISBN: 978-3-319-74913-6Published: 20 April 2018
Softcover ISBN: 978-3-030-09103-3Published: 26 January 2019
eBook ISBN: 978-3-319-74914-3Published: 11 April 2018
Series ISSN: 2190-5053
Series E-ISSN: 2190-5061
Edition Number: 1
Number of Pages: XXI, 157
Number of Illustrations: 5 b/w illustrations, 28 illustrations in colour
Topics: Catalysis, Organic Chemistry, Medicinal Chemistry