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Recent Trends in Cancer Biology: Spotlight on Signaling Cascades and microRNAs

Cell Signaling Pathways and microRNAs in Cancer Biology

  • Book
  • © 2018

Overview

Editors:
  1. Sundas Fayyaz

    1. Department of Biochemistry, Rashid Latif Medical College (RLMC), Lahore, Pakistan

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    You can also search for this editor in PubMed   Google Scholar

  2. Ammad Ahmad Farooqi

    1. Institute of Biomedical and Genetic Engineering (IBGE), Islamabad, Pakistan

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Features cutting-edge coverage and translational perspective;

  • Provides mechanistic insights and most recent ‘bench to bedside and back’ breakthroughs;

  • Different chapters of the book are written by an international panel of researchers, specialists and practitioners in the field;

  • This book presents a much-needed conceptual synthesis of the rapidly evolving field of molecular oncology;

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Table of contents (16 chapters)

  1. Front Matter

    Pages i-xii
    Download chapter PDF

  2. From Endometriosis to Cancer: Spotlight on Intracellular Signaling Cascades and MicroRNAs

    • Talha Abdul Halim, Rukset Attar, Cristina Donfrancesco, Ammad Ahmad Farooqi, Farrukh Zaman
    Pages 1-10

  3. Tyrosine Kinases, microRNAs, Epigenetics: New Insights in the Mechanisms of Leukemogenesis

    • Maria Ciccone, George A. Calin
    Pages 11-25

  4. The Emerging Role of Exosomes in Cancer Progression and Their Potential as Therapy Targets

    • Carolina F. Ruivo, Sónia A. Melo
    Pages 27-45

  5. Tranquilizing and Awakening ATM to Promote Killing of Cancer Cells

    • Yi Chieh Lim, Shahzad Bhatti, Ammad Ahmad Farooqi
    Pages 47-58

  6. The Role of GPER Signaling in Carcinogenesis: A Focus on Prostate Cancer

    • Marília I. Figueira, Henrique J. Cardoso, Sílvia Socorro
    Pages 59-117

  7. Bone Cancer: Dysregulation of Signaling Cascades by microRNAs

    • Janaina de Andréa Dernowsek
    Pages 119-128

  8. The Roles of miR-25 and Its Targeted Genes in Human Cancer

    • Carmen Caiazza, Palmiro Poltronieri, Massimo Mallardo
    Pages 129-139

  9. Notch Signaling in Lung Cancer Initiation and Development

    • Kayla C. Lewis, Yi Liu
    Pages 141-149

  10. TGF-β/Smad Signalling Pathway in Cancer

    • Mohadeseh Hasanpourghadi, Mohd. Rais Mustafa
    Pages 151-185

  11. Natural Agents Mediated Regulation of microRNAs: Do We Need Skilled Archers to Hit the Bullseye

    • Eun Jung Sohn, Ammad Ahmad Farooqi, Hwan Tae Park
    Pages 187-197

  12. Sebaceous Carcinoma of the Eyelid

    • Armando Luis Garcia, Ke Jin, Ravi Doddapaneni, Catherine Jeeyun Choi, Maria Paula Fernandez, Sander Dubovy et al.
    Pages 199-220

  13. Current Knowledge of miRNAs as Biomarkers in Breast Cancer

    • Maria Luisa Gasparri, Zein Mersini Besharat, Aris Raad Besharat, Ilary Ruscito, Konstantinos Nirgianakis, Ammad Ahmad Farooqi et al.
    Pages 221-231

  14. Signaling Landscape of AML: The Story So Far

    • Chiara Martinelli
    Pages 233-262

  15. When the Molecules Start Playing Chess, or How MicroRNAs Acquire Dualistic Activity During Cancer Progression

    • Krassimira Todorova, Soren Hayrabedyan
    Pages 263-277

  16. The Crosstalk Between miRNAs and Autophagy in Cancer Progression

    • Bayraktar Oznur, Gozuacik Devrim
    Pages 279-291

  17. Role of CEACAM in Different Cancers

    • Ilhan Yaylim, Ghazala Butt, Sumbul Khalid, Ammad Ahmad Farooqi
    Pages 293-300

  18. Back Matter

    Pages 301-308
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Keywords

About this book

Cancer is a multifaceted disease and overwhelmingly increasing experimental evidence has helped us to develop a deeper understanding of the role of signal transduction cascades in cancer development and progression. Tissue microarrays and next generation sequencing technologies have assisted us to gather missing pieces of jigsaw puzzle and we now know that deregulation of spatio-temporally controlled signaling cascades play fundamental role in metastasis and resistance against wide ranging therapeutics.


This book offers a balanced overview of the rapidly emerging cutting edge research in molecular oncology and good source of knowledge for established oncologists, basic and medical students and pharmaceutical industry associated R&D departments.

Editors and Affiliations

  • Department of Biochemistry, Rashid Latif Medical College (RLMC), Lahore, Pakistan

    Sundas Fayyaz

  • Institute of Biomedical and Genetic Engineering (IBGE), Islamabad, Pakistan

    Ammad Ahmad Farooqi

About the editors

Sundas Fayyaz is working as a Scientist in research laboratory of Rashid Latif Medical College (RLMC). Her expertise lies in cancer genetics and therapeutics. 


Ammad Ahmad Farooqi is currently a Senior Scientist at the Institute of Biomedical and Genetic Engineering (IBGE), in Islamabad, Pakistan. His area of research is tightly focused on cancer genetics and therapeutics.

Bibliographic Information

  • Book Title: Recent Trends in Cancer Biology: Spotlight on Signaling Cascades and microRNAs

  • Book Subtitle: Cell Signaling Pathways and microRNAs in Cancer Biology

  • Editors: Sundas Fayyaz, Ammad Ahmad Farooqi

  • DOI: https://doi.org/10.1007/978-3-319-71553-7

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer International Publishing AG, part of Springer Nature 2018

  • Hardcover ISBN: 978-3-319-71552-0Published: 16 March 2018

  • Softcover ISBN: 978-3-030-10074-2Published: 26 January 2019

  • eBook ISBN: 978-3-319-71553-7Published: 07 March 2018

  • Edition Number: 1

  • Number of Pages: XII, 308

  • Number of Illustrations: 16 illustrations in colour

  • Topics: Cancer Research, Molecular Medicine

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