Overview
- Discusses the question of long-term, persistent Chlamydia infection
- Provides new insights into chlamydial host adaptation
- Illustrates the complex mechanisms that determine immune recognition, immunopathology and potentially anti-infective protection
Part of the book series: Current Topics in Microbiology and Immunology (CT MICROBIOLOGY, volume 412)
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Table of contents (9 chapters)
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Front Matter
Keywords
About this book
The genus Chlamydia encompasses a number of species of obligate intracellular bacteria, including important human pathogens like the most common bacterial agent of sexually transmitted disease. This volume reviews current knowledge of chlamydial biology, covering the unusual structure of the bacteria – which alternate between metabolically almost inactive and fast-dividing forms. It also discusses the ways in which Chlamydia manipulates the host cytoskeleton and subverts the host cell’s defence, and illustrates how genomics have begun to uncover the diversity and complexity of chlamydial strains that look very similar but may cause distinct forms of disease. Further, it describes how techniques are now finally being established that can genetically modify Chlamydia, and discusses why such modification is still very difficult and what progress we can expect. Lastly, it presents our current understanding of chlamydial disease: what do we know about chronic infections, what are the mechanisms of inflammatory damage, and what are the prospects of a vaccine? Written be specialists in these various areas, the book is a valuable work of reference for students and scientists with an interest in the molecular, cellular and immunobiology of these fascinating bacteria.
Editors and Affiliations
About the editor
Prof. Dr. med. Georg Häcker
Universitätsklinikum Freiburg
Institut für Medizinische Mikrobiologie und Hygiene
Hermann-Herder-Str. 11
79104 Freiburg
Germany
e-mail: Georg.Haecker@uniklinik-freiburg.de
Phone: +49 761 203-6531
Bibliographic Information
Book Title: Biology of Chlamydia
Editors: Georg Häcker
Series Title: Current Topics in Microbiology and Immunology
DOI: https://doi.org/10.1007/978-3-319-71232-1
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer International Publishing AG, part of Springer Nature 2018
Hardcover ISBN: 978-3-319-71230-7Published: 09 July 2018
Softcover ISBN: 978-3-030-10031-5Published: 09 February 2019
eBook ISBN: 978-3-319-71232-1Published: 25 June 2018
Series ISSN: 0070-217X
Series E-ISSN: 2196-9965
Edition Number: 1
Number of Pages: X, 237
Topics: Medical Microbiology, Immunology, Infectious Diseases