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Biomimetics Through Nanoelectronics

Development of Three Dimensional Macroporous Nanoelectronics for Building Smart Materials, Cyborg Tissues and Injectable Biomedical Electronics

  • Book
  • © 2018

Overview

Authors:
  1. Jia Liu

    1. Department of Chemistry and Chemical Biology, Harvard University, Cambridge, USA

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  • Nominated as an outstanding Ph.D. thesis by Harvard University, Massachusetts, USA
  • Describes how nanoelectronics that mimic biomaterials can be seamlessly integrated with living systems
  • Introduces techniques for constructing half-machine, half-living systems, which is considered the beginning of the cyborg era
  • Includes the first realization of "neural lace" technique once described by science fiction "Culture Series"
  • Includes supplementary material: sn.pub/extras

Part of the book series: Springer Theses (Springer Theses)

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Table of contents (6 chapters)

  1. Front Matter

    Pages i-xx
    Download chapter PDF

  2. Introduction

    • Jia Liu
    Pages 1-14

  3. Three-Dimensional Macroporous Nanoelectronics Network

    • Jia Liu
    Pages 15-25

  4. Integration of Three-Dimensional Macroporous Nanoelectronics with Materials

    • Jia Liu
    Pages 27-38

  5. Three-Dimensional Macroporous Nanoelectronics Scaffold Innervated Synthetic Tissue

    • Jia Liu
    Pages 39-63

  6. Syringe Injectable Electronics

    • Jia Liu
    Pages 65-93

  7. Outlook

    • Jia Liu
    Pages 95-98
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Keywords

About this book

This thesis presents original research on how to seamlessly integrate electronics with living biological systems. Jia Liu has used silicon nanowires as active sensors to investigate biological signals at the cellular level. He has also designed nanoelectronic networks into flexible, three-dimensional (3D) and macroporous architectures, which mimic the structure of tissue scaffolds for in vitro 3D integrations with synthetic tissues and in vivo implantation by means of syringe injection. Importantly, the results demonstrate 3D interpenetrations of nanoelectronic networks with neural networks, 3D mapping of tissue activity and long-term implantation with minimal immunoresponses. Further, the book discusses potential applications for pharmacological studies, brain activity mapping and nanoelectronics enabled therapies. The findings presented here have gained wide recognition, including a top research ranking by Chemical & Engineering News and being listed among Scientific American’s10 world changing ideas in 2015.

Authors and Affiliations

  • Department of Chemistry and Chemical Biology, Harvard University, Cambridge, USA

    Jia Liu

About the author

Jia Liu received his Ph.D. degree in Chemistry from Harvard University in 2014. His Ph.D. research with Prof. Charles M. Lieber included the fundamental studies of high performance silicon nanowire field-effect transistors and their applications in three-dimensional soft nanoelectronics, regenerative medicine, neuroscience and neuroengineering. He is now working as postdoctoral fellow with Profs. Zhenan Bao, Karl Deisseroth and Anson Lee at Stanford University to develop soft electronic systems for wearable technology, patient-specific cardiac diagnosis and genetically-targeted brain-machine interface.

Bibliographic Information

  • Book Title: Biomimetics Through Nanoelectronics

  • Book Subtitle: Development of Three Dimensional Macroporous Nanoelectronics for Building Smart Materials, Cyborg Tissues and Injectable Biomedical Electronics

  • Authors: Jia Liu

  • Series Title: Springer Theses

  • DOI: https://doi.org/10.1007/978-3-319-68609-7

  • Publisher: Springer Cham

  • eBook Packages: Chemistry and Materials Science, Chemistry and Material Science (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2018

  • Hardcover ISBN: 978-3-319-68608-0Published: 29 November 2017

  • Softcover ISBN: 978-3-319-88631-2Published: 27 May 2018

  • eBook ISBN: 978-3-319-68609-7Published: 16 November 2017

  • Series ISSN: 2190-5053

  • Series E-ISSN: 2190-5061

  • Edition Number: 1

  • Number of Pages: XX, 98

  • Number of Illustrations: 48 illustrations in colour

  • Topics: Nanochemistry, Biotechnology, Biomaterials

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