Intracranial Pressure & Neuromonitoring XVI

1. Front Matter

   Pages i-xii

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2. Traumatic Brain Injury

   1. Front Matter

      Pages 1-1

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   2. Cerebral Perfusion Pressure Variability Between Patients and Between Centres

      • Bart Depreitere, Fabian Güiza, Ian Piper, Giuseppe Citerio, Iain Chambers, Patricia A. Jones et al.

      Pages 3-6

   3. Pre-hospital Predictors of Impaired ICP Trends in Continuous Monitoring of Paediatric Traumatic Brain Injury Patients

      • Adam M. H. Young, Joseph Donnelly, Xiuyun Liu, Mathew R. Guilfoyle, Melvin Carew, Manuel Cabeleira et al.

      Pages 7-10

   4. Prognosis of Severe Traumatic Brain Injury Outcomes in Children

      • Semen V. Meshcheryakov, Zhanna B. Semenova, Valery I. Lukianov, Elena G. Sorokina, Olga V. Karaseva

      Pages 11-16

   5. Do ICP-Derived Parameters Differ in Vegetative State from Other Outcome Groups After Traumatic Brain Injury?

      • Marek Czosnyka, Joseph Donnelly, Leanne Calviello, Peter Smielewski, David K. Menon, John D. Pickard

      Pages 17-20

   6. Cerebral Arterial Compliance in Traumatic Brain Injury

      • Michael Dobrzeniecki, Alex Trofimov, Denis E. Bragin

      Pages 21-24

   7. The Cerebrovascular Resistance in Combined Traumatic Brain Injury with Intracranial Hematomas

      • Alex O. Trofimov, George Kalentyev, Oleg Voennov, Michail Yuriev, Darya Agarkova, Svetlana Trofimova et al.

      Pages 25-28

   8. Computed Tomography Indicators of Deranged Intracranial Physiology in Paediatric Traumatic Brain Injury

      • Adam M. H. Young, Joseph Donnelly, Xiuyun Liu, Mathew R. Guilfoyle, Melvin Carew, Manuel Cabeleira et al.

      Pages 29-34

   9. Mean Square Deviation of ICP in Prognosis of Severe TBI Outcomes in Children

      • Zhanna B. Semenova, V. I. Lukianov, S. V. Meshcheryakov, L. M. Roshal

      Pages 35-37

   10. KidsBrainIT: A New Multi-centre, Multi-disciplinary, Multi-national Paediatric Brain Monitoring Collaboration

       • T. Lo, I. Piper, B. Depreitere, G. Meyfroidt, M. Poca, J. Sahuquillo et al.

       Pages 39-45

   11. Increased ICP and Its Cerebral Haemodynamic Sequelae

       • Joseph Donnelly, Marek Czosnyka, Spencer Harland, Georgios V. Varsos, Danilo Cardim, Chiara Robba et al.

       Pages 47-50

   12. What Determines Outcome in Patients That Suffer Raised Intracranial Pressure After Traumatic Brain Injury?

       • Samuel Patrick Klein, Bart Depreitere

       Pages 51-54

   13. Visualisation of the ‘Optimal Cerebral Perfusion’ Landscape in Severe Traumatic Brain Injury Patients

       • Ari Ercole, Peter Smielewski, Marcel J. H. Aries, Robin Wesselink, Jan Willem J. Elting, Joseph Donnelly et al.

       Pages 55-58

   14. Is There a Relationship Between Optimal Cerebral Perfusion Pressure-Guided Management and PaO2/FiO2 Ratio After Severe Traumatic Brain Injury?

       • M. Moreira, D. Fernandes, E. Pereira, E. Monteiro, R. Pascoa, C. Dias

       Pages 59-62

   15. Cognitive Outcomes of Patients with Traumatic Bifrontal Contusions

       • George Kwok Chu Wong, Karine Ngai, Wai Sang Poon, Vera Zhi Yuan Zheng, Carlos Yu

       Pages 63-65

3. Brain Monitoring Technology

   1. Front Matter

      Pages 67-67

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   2. Non-invasive Intracranial Pressure Assessment in Brain Injured Patients Using Ultrasound-Based Methods

      • Chiara Robba, Danilo Cardim, Tamara Tajsic, Justine Pietersen, Michael Bulman, Frank Rasulo et al.

      Pages 69-73

   3. Analysis of a Minimally Invasive Intracranial Pressure Signals During Infusion at the Subarachnoid Spinal Space of Pigs

      • G. Frigieri, R. A. P. Andrade, C. C. Wang, D. Spavieri Jr., L. Lopes, R. Brunelli et al.

      Pages 75-77

   4. Comparison of Different Calibration Methods in a Non-invasive ICP Assessment Model

      • Bernhard Schmidt, Danilo Cardim, Marco Weinhold, Stefan Streif, Damian D. McLeod, Marek Czosnyka et al.

      Pages 79-84

This book introduces the latest advances relating to the pathophysiology, biophysics, monitoring and treatment of traumatic brain injury, hydrocephalus, and stroke presented at the 16th International Conference on Intracranial Pressure and Neuromonitoring (the "ICP Conference"), held in Cambridge, Massachusetts, in June 2016 in conjunction with the 6th Annual Meeting of the Cerebral Autoregulation Research Network. Additionally, the conference held special sessions on neurocritical care informatics and cerebrovascular autoregulation. The peer-reviewed papers included were written by leading experts in neurosurgery, neurointensive care, anesthesiology, physiology, clinical engineering, clinical informatics and mathematics who have made important contributions in this translational area of research, and their focus ranges from the latest research findings and developments to clinical trials and experimental studies. The book continues the proud tradition of publishing key work from the ICP Conferences and is a must-read for anyone wishing to stay abreast of recent advances in the field.

• Intracranial pressure
• Neurocritical care
• Cerebral autoregulation
• Hydrocephalus
• Traumatic brain injury
• Stroke

“This book will be of most interest to bioengineers interested in cerebrovascular autoregulation, CSF biophysics, and physiological monitoring of the brain. It also will be of some interest to academic neurotraumatologists and neurointensivists. … The editor has provided an index of key words at the end of the book, referred to as a 'subject index' that will efficiently take the reader directly to the studies of interest to them.” (DonaldW. Marion, Neurosurgery, Vol. 84 (4), April, 2019)

• Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, USA

  Thomas Heldt

Thomas Heldt is the W.M. Keck Career Development Professor in Biomedical Engineering at MIT’s Institute for Medical Engineering & Science. He is also an Associate Professor of Electrical and Biomedical Engineering in MIT’s Department of Electrical Engineering & Computer Science and a Principal Investigator with MIT’s Research Laboratory of Electronics where he directs the Integrative Neuromonitoring and Critical Care Informatics Group.  

Dr. Heldt studied Physics at Johannes Gutenberg University, Germany, at Yale University, and MIT. In 2004, he received the PhD degree in Medical Physics from MIT's Division of Health Sciences and Technology and commenced postdoctoral training at MIT's Laboratory for Electromagnetic and Electronics Systems.

Dr. Heldt's research interests focus on signal processing, mathematical modeling, and model identification to support real-time clinical decision making, monitoring of disease

progression, and titration of therapy, primarily in neurocritical and neonatal critical care. In particular, Dr. Heldt is interested in developing a mechanistic understanding of physiologic systems, and in formulating appropriately chosen computational physiologic models for improved patient care. His research is conducted in close collaboration with colleagues at MIT and clinicians from Boston-area hospitals.

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