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Biomedical Technology

Modeling, Experiments and Simulation

  • Book
  • © 2018

Overview

Editors:
  1. Peter Wriggers

    1. Institute of Continuum Mechanics, Leibniz Universität Hannover, Hannover, Germany

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    You can also search for this editor in PubMed   Google Scholar

  2. Thomas Lenarz

    1. Hals-Nasen-Ohrenklinik, Medical School Hannover, Hannover, Germany

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Summarizes recent advances from scientists actively engaged in biomedical technologies
  • Focuses on implants and implant design
  • Presents modeling schemes applied to human brain tissue, blood perfusion, arterial fluid structure interaction, and drug delivery systems
  • Includes supplementary material: sn.pub/extras

Part of the book series: Lecture Notes in Applied and Computational Mechanics (LNACM, volume 84)

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Table of contents (19 chapters)

  1. Front Matter

    Pages i-ix
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  3. Cardiovascular Medicine

    1. Front Matter

      Pages 65-65
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    2. Multiscale Multiphysic Approaches in Vascular Hemodynamics

      • Michael Neidlin, Tim A S Kaufmann, Ulrich Steinseifer, Thomas Schmitz-Rode
      Pages 67-76

    3. Heart Valve Flow Computation with the Space–Time Slip Interface Topology Change (ST-SI-TC) Method and Isogeometric Analysis (IGA)

      • Kenji Takizawa, Tayfun E. Tezduyar, Takuya Terahara, Takafumi Sasaki
      Pages 77-99

    4. Estimation of Element-Based Zero-Stress State in Arterial FSI Computations with Isogeometric Wall Discretization

      • Kenji Takizawa, Tayfun E. Tezduyar, Takafumi Sasaki
      Pages 101-122

    5. Fluid-Structure Interaction Modeling in 3D Cerebral Arteries and Aneurysms

      • Yue Yu
      Pages 123-146

    6. Large-Eddy Simulation of Turbulence in Cardiovascular Flows

      • F. Nicoud, C. Chnafa, J. Siguenza, V. Zmijanovic, S. Mendez
      Pages 147-167

    7. Computational Comparison Between Newtonian and Non-Newtonian Blood Rheologies in Stenotic Vessels

      • Bruno Guerciotti, Christian Vergara
      Pages 169-183

    8. Artificial Textile Reinforced Tubular Aortic Heart Valves—Multi-scale Modelling and Experimental Validation

      • Deepanshu Sodhani, R. Varun Raj, Jaan Simon, Stefanie Reese, Ricardo Moreira, Valentine Gesché et al.
      Pages 185-215

    9. Preliminary Monolithic Fluid Structure Interaction Model for Ventricle Contraction

      • D. Cerroni, D. Giommi, S. Manservisi, F. Mengini
      Pages 217-231

    10. The Biomechanical Rupture Risk Assessment of Abdominal Aortic Aneurysms—Method and Clinical Relevance

      • T. Christian Gasser
      Pages 233-253

  4. Dentistry

    1. Front Matter

      Pages 255-255
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    2. A Deeper Insight of a Multi-dimensional Continuum Biofilm Growth Model: Experimental Observation and Parameter Studies

      • Dianlei Feng, Henryke Rath, Insa Neuweiler, Nico Stumpp, Udo Nackenhorst, Meike Stiesch
      Pages 257-272

    3. Multiscale Experimental and Computational Investigation of Nature’s Design Principle of Hierarchies in Dental Enamel

      • Songyun Ma, Ingo Scheider, Ezgi D. Yilmaz, Gerold A. Schneider, Swantje Bargmann
      Pages 273-291

  5. Orthopaedics

    1. Front Matter

      Pages 293-293
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Keywords

About this book

This book provides an overview of new mathematical models, computational simulations and experimental tests in the field of biomedical technology, and covers a wide range of current research and challenges. The first part focuses on the virtual environment used to study biological systems at different scales and under multiphysics conditions. In turn, the second part is devoted to modeling and computational approaches in the field of cardiovascular medicine, e.g. simulation of turbulence in cardiovascular flow, modeling of artificial textile-reinforced heart valves, and new strategies for reducing the computational cost in the fluid-structure interaction modeling of hemodynamics. The book’s last three parts address experimental observations, numerical tests, computational simulations, and multiscale modeling approaches to dentistry, orthopedics and otology. Written by leading experts, the book reflects the remarkable advances that have been made in the field of medicine, the life sciences, engineering and computational mechanics over the past decade, and summarizes essential tools and methods (such as virtual prototyping of medical devices, advances in medical imaging, high-performance computing and new experimental test devices) to enhance medical decision-making processes and refine implant design. The contents build upon the International Conference on Biomedical Technology 2015 (ICTB 2015), the second ECCOMAS thematic conference on Biomedical Engineering, held in Hannover, Germany in October 2015.

Editors and Affiliations

  • Institute of Continuum Mechanics, Leibniz Universität Hannover, Hannover, Germany

    Peter Wriggers

  • Hals-Nasen-Ohrenklinik, Medical School Hannover, Hannover, Germany

    Thomas Lenarz

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